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Neonatal stroke in mice causes long-term changes in neuronal notch-2 expression that may contribute to prolonged injury

Albéri, Lavinia ; Chi, Zhikai ; Kadam, Shilpa D. ; Mulholland, Justin D. ; Dawson, Valina L. ; Gaiano, Nicholas ; Comi, Anne M.

In: Stroke, 2010, vol. 41, no. Suppl. 1, p. S64-S71

Background and Purpose: Notch receptors (1–4) are membrane proteins that, on ligand stilumation, release their cytoplasmic domains to serve as transcription factors. Notch-2 promotes proliferation both during development and cancer, but its role in response to ischemic injury is less well understood. The purpose of this study was to understand whether Notch-2 is induced after neonatal stroke...

Estrogen dependent expression of the receptor tyrosine kinase axl in normal and malignant human breast

Berclaz, G. ; Altermatt, H. J. ; Rohrbach, V. ; Kieffer, I. ; Dreher, E. ; Andres, A.-C

In: Annals of Oncology, 2001, vol. 12, no. 6, p. 819-824

New knowledge about T-cell cytotoxicity

Cerottini, J.-C ; Tschopp, J.

In: Annals of Oncology, 1997, vol. 8, p. S75-S78

Glucocorticoids Exert Direct Toxicity on Microvasculature: Analysis of Cell Death Mechanisms

El Zaoui, Ikram ; Behar-Cohen, Francine ; Torriglia, Alicia

In: Toxicological Sciences, 2015, vol. 143, no. 2, p. 441-453

Mechanisms of Hepatocellular Toxicity Associated with Dronedarone—A Comparison to Amiodarone

Felser, Andrea ; Blum, Kim ; Lindinger, Peter W. ; Bouitbir, Jamal ; Krähenbühl, Stephan

In: Toxicological Sciences, 2013, vol. 131, no. 2, p. 480-490

Specific targeting of human caspases using designed ankyrin repeat proteins

Flütsch, Andreas ; Schroeder, Thilo ; Barandun, Jonas ; Ackermann, Rafael ; Bühlmann, Martin ; Grütter, Markus G.

In: Biological Chemistry, 2014, vol. 395, no. 10, p. 1243-1252

Different vascular smooth muscle cell apoptosis in the human internal mammary artery and the saphenous vein: implications for bypass graft disease

Frischknecht, Karin ; Greutert, Helen ; Weisshaupt, Christian ; Kaspar, Mathias ; Yang, Zhihong ; Lüscher, Thomas F. ; Carrel, Thierry P. ; Tanner, Felix C.

In: Journal of Vascular Research, 2006, vol. 43, no. 4, p. 338-346

The remarkable patency of internal mammary artery (MA) grafts compared to saphenous vein (SV) grafts has been related to different biological properties of the two blood vessels. We examined whether proliferation and apoptosis of vascular smooth muscle cells (VSMC) from human coronary artery bypass vessels differ according to patency rates. Methods and Results: Proliferation rates to serum...

Regulated overexpression of the survival factor bcl-2 in CHO cells increases viable cell density in batch culture and decreases DNA release in extended fixed-bed cultivation

Fussenegger, Martin ; Fassnacht, Dieter ; Schwartz, Regine ; Zanghi, James ; Graf, Michael ; Bailey, James ; Pörtner, Ralf

In: Cytotechnology, 2000, vol. 32, no. 1, p. 45-61

Membrane translocation and oligomerization of hBok are triggered in response to apoptotic stimuli and Bnip3

Gao, S. ; Fu, W. ; Dürrenberger, M. ; Geyter, C. ; Zhang, H.

In: Cellular and Molecular Life Sciences CMLS, 2005, vol. 62, no. 9, p. 1015-1024

Role of phosphoinositide 3-kinase in the autophagic death of serum-deprived PC12 cells

Guillon-Munos, A. ; van Bemmelen, M. ; Clarke, P.

In: Apoptosis, 2005, vol. 10, no. 5, p. 1031-1041