In: Health Promotion International, 2018, vol. 33, no. 3, p. 378-389
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In: The American Journal of Clinical Nutrition, 2017, vol. 105, no. 2, p. 513-525
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In: Aging, 2010, vol. 2, no. 7, p. 387-389
Dietary restriction (DR), reduced food uptake without malnutrition, is the most universal intervention known to extend animal lifespan, from invertebrates to mammals [1]. However, despite impressive progress in identifying the key components of the DR pathway, many proximal effectors of DR induced longevity remain unknown to date [1]. One central obstacle in the search for such mechanisms is...
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In: Nature, 2009, vol. 462, no. 24, p. 989-990
Dietary restriction promotes longevity but impairs fecundity in many organisms. When the amino acids in a diet are fine-tuned, however, lifespan can be increased without loss of fecundity — at least in fruitflies.
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In: Science, 2007, vol. 318, p. 1255-1256
A theory of trade-offs to explain why we age has spurred 50 years of interdisciplinary research in evolution and molecular genetics.
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In: Experimental Gerontology, 2006, vol. 42, no. 3, p. 247-251
The extension of life span by diet restriction in Drosophila has been argued to occur without limiting calories. Here we directly measure the calories assimilated by flies when maintained on full- and restricted-diets. We find that caloric intake is reduced on all diets that extend life span. Flies on low-yeast diet are long-lived and consume about half the calories of flies on high-yeast diets,...
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In: Zeitschrift für Gerontologie und Geriatrie, 2005, vol. 38, no. 5, p. 334-341
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In: JNHA - The Journal of Nutrition, Health and Aging, 2009, vol. 13, no. 6, p. 491-497
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In: Prehospital and Disaster Medicine, 2005, vol. 20, no. 6, p. 385-388
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In: Primary Health Care Research & Development, 2008, vol. 9, no. 3, p. 191-198
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