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Université de Fribourg

Full genome sequence of pT3, a multiresistant plasmid carrying the mcr-3.5 colistin resistance gene, recovered from an extended-spectrum-β-lactamase-producing Escherichia coli isolate from crickets sold as food

Zurfluh, Katrin ; Stevens, Marc J. A. ; Bucher, Melissa ; Poirel, Laurent ; Nordmann, Patrice ; Stephan, Roger

In: Microbiology Resource Announcements, 2019/8/29/e00647-19, /mra/8/29/MRA.00647-19.atom

Here, we sequenced multidrug resistance plasmid pT3, which encodes mcr-3.5 and other resistance genes. The cooccurrence of mcr genes and other resistance genes on a single plasmid is of concern.

Université de Fribourg

Key features of mcr-1-bearing plasmids from Escherichia coli isolated from humans and food

Zurfluh, Katrin ; Nüesch-Inderbinen, Magdalena ; Klumpp, Jochen ; Poirel, Laurent ; Nordmann, Patrice ; Stephan, Roger

In: Antimicrobial Resistance & Infection Control, 2017, vol. 6, p. 91

Mcr-1-harboring Enterobacteriaceae are reported worldwide since their first discovery in 2015. However, a limited number of studies are available that compared full-length plasmid sequences of human and animal origins.

Université de Fribourg

Screening for fecal carriage of MCR-producing Enterobacteriaceae in healthy humans and primary care patients

Zurfluh, Katrin ; Stephan, Roger ; Widmer, Andreas ; Poirel, Laurent ; Nordmann, Patrice ; Nüesch, Hans-Jakob ; Hächler, Herbert ; Nüesch-Inderbinen, Magdalena

In: Antimicrobial Resistance & Infection Control, 2017, vol. 6, p. 28

The objective of this study was to test the efficacy of an inhibitor of the New Delhi metallo-β- lactamase (NDM-1). Inhibiting expression of this type of antibiotic-resistance gene has the potential to restore antibiotic susceptibility in all bacteria carrying the gene.Methods: We have constructed a peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO) that selectively inhibits...

Université de Fribourg

First detection of Klebsiella variicola producing OXA-181 carbapenemase in fresh vegetable imported from Asia to Switzerland

Zurfluh, K. ; Poirel, Laurent ; Nordmann, Patrice ; Klumpp, J. ; Stephan, R.

In: Antimicrobial Resistance and Infection Control, 2015, vol. 4, p. 38

Background: The emergence and worldwide spread of carbapenemase-producing Enterobacteriaceae is of great concern to public health services. The aim of this study was to investigate the occurrence of carbapenemase-producing Enterobacteriaceae in fresh vegetables and spices imported from Asia to Switzerland.Findings: Twenty-two different fresh vegetable samples were purchased in March 2015 from...

Université de Fribourg

Plant development regulated by cytokinin sinks

Zürcher, Evelyne ; Liu, Jingchun ; Donato, Martin di ; Geisler, Markus ; Müller, Bruno

In: Science, 2016, vol. 353, no. 6303, p. 1027–1030

Morphogenetic signals control the patterning of multicellular organisms. Cytokinins are mobile signals that are perceived by subsets of plant cells. We found that the responses to cytokinin signaling during Arabidopsis development are constrained by the transporter PURINE PERMEASE 14 (PUP14). In our experiments, the expression of PUP14 was inversely correlated to the cytokinin signaling...

Université de Fribourg

Rezensionen - Mario Turchetti: Tyrannie et tyrannicide de l'Antiquité à nos jours - PUF 2001

Zurbuchen, Simone

In: Zur Entwicklungsgeschichte moralischer Grund-Sätze in der Philosophie der Aufklärung = The development of moral first principles in the philosophy of the Enlightenment, 2004, vol. 12, p. 540-542

Université de Fribourg

Fat oxidation kinetics is related to muscle deoxygenation kinetics during exercise

Zurbuchen, Anouck ; Lanzi, Stefano ; Voirol, Ludovic ; Trindade, Cybele Barboza ; Gojanovic, Boris ; Kayser, Bengt ; Bourdillon, Nicolas ; Chenevière, Xavier ; Malatesta, Davide

In: Frontiers in Physiology, 2020, vol. 11, p. -

The present study aimed to determine whether whole-body fat oxidation and muscle deoxygenation kinetics parameters during exercise were related in individuals with different aerobic fitness levels.Methods: Eleven cyclists [peak oxygen uptake (V.O2peak): 64.9 ± 3.9 mL⋅kg–1⋅min–1] and 11 active individuals (V.O2peak: 49.1 ± 7.4 mL⋅kg–1⋅min–1) performed a maximal incremental...

Consortium of Swiss Academic Libraries

Unscharfe Klassifikation von Webkennzahlen

Zumstein, Darius ; Hugi, Patrik

In: HMD Praxis der Wirtschaftsinformatik, 2009, vol. 46, no. 4, p. 44-56

Université de Fribourg

Little ice age glacier history of the central and western alps from pictorial documents

Zumbühl, Heinz J. ; Nussbaumer, Samuel U.

In: Cuadernos de Investigación Geográfica, 2018, vol. 44, no. 1, p. 115–136

The Lower Grindelwald Glacier (Bernese Oberland, Switzerland) consists of two parts, the Ischmeer in the east (disconnected) and the Bernese Fiescher Glacier in the west. During the Little Ice Age (LIA), the glacier terminated either in the area of the “Schopffelsen” (landmark rock terraces) or advanced at least six times (ten times if we include early findings) even further down into the...

Université de Fribourg

Phase behavior of selected artificial lipids

Zumbuehl, Andreas ; Dobner, Bodo ; Brezesinski, Gerald

In: Current Opinion in Colloid & Interface Science, 2014, vol. 19, no. 1, p. 17–24

The flexibility of biomembranes is based on the physical-chemical properties of their main components - glycerophospholipids. The structure of these modular amphiphilic molecules can be modified through organic synthesis making it possible to study specific physical-chemical effects in detail. In particular, the roles of the hydrophobic tails of the phospholipids and their...