In: Muscle & Nerve, 2010, vol. 41, no. 3, p. 399 - 405
Long-term disturbance of the calcium homeostasis of motor endplates (MEPs) causes necrosis of muscle fibers. The onset of morphological changes in response to this disturbance, particularly in relation to the fiber type, is presently unknown. Omohyoid muscles of mice were incubated for 1-30 minutes in 0.1 mM carbachol, an acetylcholine agonist that causes an inward calcium current. In these...
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In: Physical Review A, 2009, vol. 79, no. 4, p. 042504
We perform convergent close-coupling calculations of double photoionization (DPI) of the K-shell of alkaline-earth metal atoms (Be, Mg, and Ca) from the threshold to the nonrelativistic limit of infinite photon energy. Theoretical double-to-single photoionization cross-section ratios for Mg and Ca are compared with experimental values derived from high-resolution x-ray spectra following the...
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In: Journal of Neurochemistry, 2007, vol. 100, no. 3, p. 727–735
The Ca²⁺-binding protein (CaBP) parvalbumin (PV) is strongly expressed in cerebellar Purkinje neurones (PNs). It is considered a pure Ca²⁺ buffer, lacking any Ca²⁺ sensor function. Consistent with this notion, no PV ligand was found in dendrites of PNs. Recently, however, we observed for a related CaBP that ligand-targeting differs substantially between dendrites and axons. Thus, here we...
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In: The Journal of Neuroscience, 2005, vol. 25, no. 1, p. 96-107
Certain interneurons contain large concentrations of specific Ca²⁺-binding proteins (CBPs), but consequences on presynaptic Ca²⁺ signaling are poorly understood. Here we show that expression of the slow CBP parvalbumin (PV) in cerebellar interneurons is cell specific and developmentally regulated, leading to characteristic changes in presynaptic Ca²⁺ dynamics (Cai). Using...
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