Université de Fribourg

Impairment of both languages in late bilinguals with dementia of the Alzheimer type

Manchon, Mélanie ; Buetler, Karin ; Colombo, Françoise ; Spierer, Lucas ; Assal, Frédéric ; Annoni, Jean-Marie

In: Bilingualism: Language and Cognition, 2014, vol. 18, no. 01, p. 90–100

Neuropsychological theories raise the question if in late bilinguals with dementia of the Alzheimer type (DAT), the second language (L2) may be more impaired than the first (L1). We compared language performance in different tasks of oral comprehension (semantic and syntactic) and production (naming, repetition and fluency) in L1 and L2 in a group of 13 late proficient bilinguals wit DAT...

Université de Fribourg

Developmental regulation of expression of schizophrenia susceptibility genes in the primate hippocampal formation

Favre, Guillaume ; Banta Lavenex, Pamela A. ; Lavenex, Pierre

In: Translational Psychiatry, 2012, vol. 2, p. e173

The hippocampal formation is essential for normal memory function and is implicated in many neurodevelopmental, neurodegenerative and neuropsychiatric disorders. In particular, abnormalities in hippocampal structure and function have been identified in schizophrenic subjects. Schizophrenia has a strong polygenic component, but the role of numerous susceptibility genes in normal brain development...