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Université de Fribourg

The Evolution of Aging

Fabian, Daniel ; Flatt, Thomas

In: Nature Education Knowledge, 2011, vol. 3, no. 3, p. 1-10

Université de Fribourg

Still Pondering an Age-Old Question

Flatt, Thomas ; Promislow, Daniel E. L.

In: Science, 2007, vol. 318, p. 1255-1256

A theory of trade-offs to explain why we age has spurred 50 years of interdisciplinary research in evolution and molecular genetics.

Université de Fribourg

A role for genetic accommodation in evolution?

Braendle, Christian ; Flatt, Thoams

In: BioEssays, 2006, no. 28, p. 868-873

Whether evolutionary change can occur by genetic assimilation, or more generally by genetic accommodation, remains controversial. Here we examine some of the experimental evidence for both phenomena. Several experiments in Drosophila suggest that assimilation is possible, and a new paper1 shows that a color polyphenism in the tobacco hornworm, Manduca sexta, can evolve by genetic accommodation....

Université de Fribourg

Hormonal pleiotropy and the juvenile hormone regulation of Drosophila development and life history

Flatt, Thomas ; Tu, Meng-Ping ; Tatar, Marc

In: BioEssays, 2005, vol. 27, no. 10, p. 999-1010

Understandinghowtraits are integrated at the organismal level remains a fundamental problem at the interface of developmental and evolutionary biology. Hormones, regulatory signaling molecules that coordinate multiple developmental and physiological processes, are major determinants underlying phenotypic integration. The probably best example for this is the lipid-like juvenile hormone (JH) in...

Université de Fribourg

Evolutionary origin of synapses and neurons – Bridging the gap

Burkhardt, Pawel ; Sprecher, Simon G.

In: BioEssays, 2017/39/10/n/a-n/a

The evolutionary origin of synapses and neurons is an enigmatic subject that inspires much debate. Non-bilaterian metazoans, both with and without neurons and their closest relatives already contain many components of the molecular toolkits for synapse functions. The origin of these components and their assembly into ancient synaptic signaling machineries are particularly important in light...

Université de Fribourg

Ecophylogenetics: advances and perspectives

Mouquet, Nicolas ; Devictor, Vincent ; Meynard, Christine N. ; Munoz, Francois ; Bersier, Louis Félix ; Chave, Jérôme ; Couteron, Pierre ; Dalecky, Ambroise ; Fontaine, Colin ; Gravel, Dominique ; Hardy, Olivier J. ; Jabot, Franck ; Lavergne, Sébastien ; Leibold, Mathew ; Mouillot, David ; Münkemüller, Tamara ; Pavoine, Sandrine ; Prinzing, Andreas ; Rodrigues, Ana S.L. ; Rohr, Rudolf P. ; Thébault, Elisa ; Thuiller, Wilfried

In: Biologial Review, 2012, p. -

Ecophylogenetics can be viewed as an emerging fusion of ecology, biogeography and macroevolution. This new and fast-growing field is promoting the incorporation of evolution and historical contingencies into the ecological research agenda through the widespread use of phylogenetic data. Including phylogeny into ecological thinking represents an opportunity for biologists from different fields to...

Université de Fribourg

Natural polymorphism affecting learning and memory in Drosophila

Mery, Frederic ; Belay, Amsale T. ; So, Anthony K.-C. ; Sokolowski, Marla B. ; Kawecki, Tadeusz J.

In: Proceedings of the National Academy of Sciences of the United States of America, 2007, vol. 104, no. 32, p. 13051-13055

Knowing which genes contribute to natural variation in learning and memory would help us understand how differences in these cognitive traits evolve among populations and species. We show that a natural polymorphism at the foraging (for) locus, which encodes a cGMP-dependent protein kinase (PKG), affects associative olfactory learning in Drosophila melanogaster. In an assay...