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Université de Fribourg

Natural polymorphism affecting learning and memory in Drosophila

Mery, Frederic ; Belay, Amsale T. ; So, Anthony K.-C. ; Sokolowski, Marla B. ; Kawecki, Tadeusz J.

In: Proceedings of the National Academy of Sciences of the United States of America, 2007, vol. 104, no. 32, p. 13051-13055

Knowing which genes contribute to natural variation in learning and memory would help us understand how differences in these cognitive traits evolve among populations and species. We show that a natural polymorphism at the foraging (for) locus, which encodes a cGMP-dependent protein kinase (PKG), affects associative olfactory learning in Drosophila melanogaster. In an assay...