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Saccharomyces cerevisiae, a model to study sterol uptake and transport in eukaryotes

Reiner, Sonja ; Micolod, Delphine ; Schneiter, Roger

In: Biochemical Society Transactions, 2005, vol. 33, no. 5, p. 1186-1188

The molecular mechanisms that govern intracellular transport of sterols in eukaryotic cells are only poorly understood. Saccharomyces cerevisiae is a facultative anaerobic organism that requires supplementation with unsaturated fatty acids and sterols to grow in the absence of oxygen, as the synthesis of these lipids requires molecular oxygen. The fact that yeast grows well under anaerobic...