In: British Journal of Nutrition, 2011, vol. 105, no. 12, p. 1750-1763
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In: Cahiers de Nutrition et de Diététique, 2013, vol. 48, no. 1, p. 15–25
‘Dieting Makes You Fat’ – the title of a book published in 1983 – embodies the notion that dieting to control body weight, with consequential weight cycling, predisposes the individual to acquire even more body fat. While this notion is controversial, its debate underscores the large gap, which exists in our understanding of basic physiological laws, which govern the regulation of human...
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In: British Journal of Nutrition, 2011, vol. 105, no. 12, p. 1750-1763
The present study investigates whether excessive fat accumulation and hyperinsulinaemia during catch-up growth on high-fat diets are altered by n-6 and n-3 PUFA derived from oils rich in either linoleic acid (LA), α-linolenic acid (ALA), arachidonic acid (AA) or DHA. It has been shown that, compared with food-restricted rats refed a high-fat (lard) diet low in PUFA, those...
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In: International Journal of Obesity, 2007, vol. 31, no. 2, p. 378–381
Mice lacking β-adrenoceptors, which mediate the thermogenic effects of norepinephrine and epinephrine, show diminished thermogenesis and high susceptibility to obesity, whereas mice lacking stearoyl-CoA desaturase 1 (SCD1), which catalyzes the synthesis of monounsaturated fatty acids, show enhanced thermogenesis and high resistance to obesity. In testing whether β-adrenergic...
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