In: The Handbook of the Biology of Aging, 2006, p. 415-448
This chapter reviews hormonal effects on aging in Drosophila melanogaster. The insect juvenile hormone (JH) is a sesquiterpenoid compound produced by the corpora allata (CA), a pair of endocrine glands with nervous connections to the brain. In pre- adult development and metamorphosis, JH functions as a "status quo" hormone, allowing continued growth after ecdysteroid-induced molting....
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In: BioEssays, 2005, vol. 27, no. 10, p. 999-1010
Understandinghowtraits are integrated at the organismal level remains a fundamental problem at the interface of developmental and evolutionary biology. Hormones, regulatory signaling molecules that coordinate multiple developmental and physiological processes, are major determinants underlying phenotypic integration. The probably best example for this is the lipid-like juvenile hormone (JH)...
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In: Development, 2004, vol. 131, p. 117-130
In both insects and mammals, olfactory receptor neurons (ORNs) expressing specific olfactory receptors converge their axons onto specific glomeruli, creating a spatial map in the brain. We have previously shown that second order projection neurons (PNs) in Drosophila are prespecified by lineage and birth order to send their dendrites to one of ~50 glomeruli in the antennal lobe. How can a given...
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In: Developmental Biology, 2016, vol. 410, no. 2, p. 164–177
Sensory perception of light is mediated by specialized Photoreceptor neurons (PRs) in the eye. During development all PRs are genetically determined to express a specific Rhodopsin (Rh) gene and genes mediating a functional phototransduction pathway. While the genetic and molecular mechanisms of PR development is well described in the adult compound eye, it remains unclear how the expression of...
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