Université de Fribourg

The thalamocortical projection systems in Primate : an anatomical support for multisensory and sensorimotor interplay

Cappe, Céline ; Morel, Anne ; Barone, Pascal ; Rouiller, Eric M.

In: Cerebral Cortex, 2009, vol. 19, no. 9, p. 2025-2037

Multisensory and sensorimotor integrations are usually considered to occur in superior colliculus and cerebral cortex, but few studies proposed the thalamus as being involved in these integrative processes. We investigated whether the organization of the thalamocortical (TC) systems for different modalities partly overlap, representing an anatomical support for multisensory and sensorimotor...

Université de Fribourg

Primate adult brain cell autotransplantation, a new tool for brain repair ?

Brunet, Jean-François ; Rouiller, Eric M. ; Wannier, Thierry ; Villemure, Jean-Guy ; Bloch, Jocelyne

In: Experimental Neurology, 2005, vol. 196, no. 1, p. 195-198

If successful, autologous brain cell transplantation is an attractive approach to repair lesions and restore function of the central nervous system. We demonstrate that monkey adult brain cells obtained from cortical biopsy and kept in culture for 4 weeks exhibit neural progenitor characteristics. After reimplantation into a lesion area of the donor cerebral cortex, these cells can successfully...

Université de Fribourg

A unilateral section of the corticospinal tract at cervical level in Primate does not lead to measurable cell loss in Motor cortex

Wannier, Thierry. ; Schmidlin, Eric ; Bloch, Jocelyne ; Rouiller, Eric M.

In: Journal of Neurotrauma, 2005, vol. 22(6), p. 703

The effects of a unilateral interruption of the dorsolateral funiculus at cervical level on the survival of neurons in the motor cortex were investigated in macaque monkeys. The lesion was made on the left side at the transition region between the 7th and 8th cervical segments, above the motoneurons controlling hand muscles. As a result, the homolateral hand became paretic,...