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    Université de Fribourg

    Plant pathogenesis-related proteins of the cacao fungal pathogen Moniliophthora perniciosa differ in their lipid-binding specificities

    Darwiche, Rabih ; El Atab, Ola ; Baroni, Renata Moro ; Teixeira, Paulo J. P. L. ; Mondego, Jorge M. C. ; Pereira, Gonçalo A. G. ; Schneiter, Roger

    In: Journal of Biological Chemistry, 2017, p. jbc.M117.811398

    Moniliophthora perniciosa is the causative agent of witches' broom disease, which devastates cacao cultures in South America. This pathogenic fungus infects meristematic tissues and derives nutrients from the plant apoplast during an unusually long-lasting biotrophic stage. In order to survive, the fungus produces proteins to suppress the plant immune response. Proteins of the Pathogenesis...

    Université de Fribourg

    Crystal structure of MpPR-1i, a SCP/TAPS protein from Moniliophthora perniciosa , the fungus that causes witches’ broom disease of cacao

    Baroni, Renata M. ; Luo, Zhipu ; Darwiche, Rabih ; Hudspeth, Elissa M. ; Schneiter, Roger ; Pereira, Gonçalo A. G. ; Mondego, Jorge M. C. ; Asojo, Oluwatoyin A.

    In: Scientific Reports, 2017, vol. 7, no. 1, p. 7818

    The pathogenic fungi Moniliophthora perniciosa causes Witches’ Broom Disease (WBD) of cacao. The structure of MpPR-1i, a protein expressed by M. perniciosa when it infects cacao, are presented. This is the first reported de novo structure determined by single-wavelength anomalous dispersion phasing upon soaking with selenourea. Each monomer has flexible loop regions linking the core...