Université de Fribourg

Dissemination of multiresistant Enterobacter cloacae isolates producing OXA-48 and CTX-M-15 in a Spanish hospital

Fernández, Javier ; Montero, Ignacio ; Martínez, Óscar ; Fleites, Ana ; Poirel, Laurent ; Nordmann, Patrice ; Rodicio, M. Rosario

In: International Journal of Antimicrobial Agents, 2015, vol. 46, no. 4, p. 469–474

Twenty-one multiresistant Enterobacter cloacae isolates producing OXA-48 (n = 10), CTX-M-15 (n = 7) or both (n = 4) β-lactamases were detected in a Spanish hospital during a 1-year period (June 2013 to June 2014). The isolates were also resistant to non-β-lactam antimicrobials, further complicating the therapeutic options. Genotyping of the isolates...

Université de Fribourg

KPC-producing Klebsiella pneumoniae, finally targeting Turkey

Labarca, Jaime ; Poirel, Laurent ; Özdamar, M. ; Turkoglü, S. ; Hakko, E. ; Nordmann, Patrice

In: New Microbes and New Infections, 2014, vol. 2, no. 2, p. 50–51

We report here the first identification of the worldwide spread of Klebsiella pneumoniae carbapenemase-2-producing and carbapenem-resistant K. pneumoniae clone ST258 in Turkey, a country where the distantly-related carbapenemase OXA-48 is known to be endemic. Worryingly, this isolate was also resistant to colistin, now considered to be the last-resort antibiotic for carbapenem-resistant isolates.