Université de Fribourg

Fructose ingestion acutely elevates blood pressure in healthy young humans

Brown, Clive M. ; Dulloo, Abdul G. ; Yepuri, Gayathri ; Montani, Jean-Pierre

In: American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, 2008, vol. 294, p. R730-R737

Brown, Clive M.; Division of Physiology, Department of Medicine, University of Fribourg, Switzerland Dulloo, Abdul G.; Division of Physiology, Department of Medicine, University of Fribourg, Switzerland Yepuri, Gayathri; Division of Physiology, Department of Medicine, University of Fribourg, Switzerland Montani, and Jean-Pierre; Division of Physiology, Department of Medicine, University of...

Université de Fribourg

A simple deep breathing test reveals altered cerebral autoregulation in type 2 diabetic patients

Brown, Clive M. ; Marthol, H. ; Zikeli, U. ; Ziegler, D. ; Hilz, M. J.

In: Diabetologia, 2008, vol. 51, no. 5, p. 756-761

Aims/hypothesis Patients with diabetes mellitus have an increased risk of stroke and other cerebrovascular complications. The purpose of this study was to evaluate the autoregulation of cerebral blood flow in diabetic patients using a simple method that could easily be applied to the clinical routine screening of diabetic patients.Methods We studied ten patients with type 2 diabetes mellitus and...

Université de Fribourg

Water-induced thermogenesis reconsidered: the effects of osmolality and water temperature on energy expenditure after drinking

Brown, Clive M. ; Dulloo, Abdul G. ; Montani, Jean-Pierre

In: Journal of Clinical Endocrinology and Metabolism, 2006, vol. 91, no. 9, p. 3598-3602

Context: A recent study reported that drinking 500 ml of water causes a 30% increase in metabolic rate. If verified, this previously unrecognized thermogenic property of water would have important implications for weight-loss programs. However, the concept of a thermogenic effect of water is controversial because other studies have found that water drinking does not increase energy...