Université de Fribourg

Hepatic mitochondrial energetics during catch-up fat after caloric restriction

Crescenzo, Raffaella ; Bianco, Francesca ; Falcone, Italia ; Prisco, Marina ; Dulloo, Abdul G. ; Liverini, Giovanna ; Iossa, Susanna

In: Metabolism, 2010, p. -

The objective of the study was to investigate whether changes in liver mitochondrial energetics could underlie the enhanced energetic efficiency that drives accelerated body fat recovery (catch-up fat) during refeeding after caloric restriction. Rats were subjected to caloric restriction (50% of ad libitum intake) for 15 days and then refed for 1 or 2 weeks on an amount of chow equal to that of...

Université de Fribourg

Hepatic mitochondrial energetics during catch-Up fat with high-Fat diets rich in lard or safflower oil

Crescenzo, Raffaella ; Bianco, Francesca ; Falcone, Italia ; Tsalouhidou, Sofia ; Yepuri, Gayathri ; Mougios, Vassilis ; Dulloo, Abdul G. ; Liverini, Giovanna ; Iossa, Susanna

In: Obesity, 2011, p. -

We have investigated whether altered hepatic mitochondrial energetics could explain the differential effects of high-fat diets with low or high ω6 polyunsaturated fatty acid content (lard vs. safflower oil) on the efficiency of body fat recovery (catch-up fat) during refeeding after caloric restriction. After 2 weeks of caloric restriction, rats were isocalorically refed with a low-fat diet (LF)...

Université de Fribourg

Polyunsaturated fatty acids stimulate de novo lipogenesis and improve glucose homeostasis during refeeding with high fat diet

Crescenzo, Raffaella ; Mazzoli, Arianna ; Cancelliere, Rosa ; Bianco, Francesca ; Giacco, Antonia ; Liverini, Giovanna ; Dulloo, Abdul G. ; Iossa, Susanna

In: Frontiers in Physiology, 2017, vol. 8, p. -

The recovery of body weight after a period of caloric restriction is accompanied by an enhanced efficiency of fat deposition and hyperinsulinemia—which are exacerbated by isocaloric refeeding on a high fat diet rich in saturated and monounsaturated fatty acids (SFA-MUFA), and poor in polyunsaturated fatty acids (PUFA), and associated with a blunting of de novo lipogenesis in adipose tissue...