Université de Fribourg

Stereological analysis of the rat and monkey amygdala

Chareyron, Loïc J. ; Banta Lavenex, Pamela A. ; Amaral, David G. ; Lavenex, Pierre

In: The Journal of Comparative Neurology, 2011, vol. 519, no. 16, p. 3218–3239

The amygdala is part of a neural network that contributes to the regulation of emotional behaviors. Rodents, especially rats, are used extensively as model organisms to decipher the functions of specific amygdala nuclei, in particular in relation to fear and emotional learning. Analysis of the role of the nonhuman primate amygdala in these functions has lagged work in the rodent but provides...

Université de Fribourg

Postmortem changes in the neuroanatomical characteristics of the primate brain: Hippocampal formation

Lavenex, Pierre ; Lavenex, Pamela Banta ; Bennett, Jeffrey L. ; Amaral, David G.

In: The Journal of Comparative Neurology, 2009, vol. 512, no. 1, p. 27 - 51

Comparative studies of the structural organization of the brain are fundamental to our understanding of human brain function. However, whereas brains of experimental animals are fixed by perfusion of a fixative through the vasculature, human or ape brains are fixed by immersion after varying postmortem intervals. Although differential treatments might affect the fundamental characteristics of the...

Université de Fribourg

Differential gene expression between human schwannoma and control Schwann cells

Hanemann, C. O. ; Bartelt-Kirbach, B. ; Diebold, R. ; Kämpchen, K. ; Langmesser, Sonja ; Utermark, T.

In: Neuropathology and Applied Neurobiology, 2006, vol. 32, no. 6, p. 605–614

The NF2 gene encodes the tumour suppressor protein merlin. The mutation of a single allele of this gene causes the autosomal dominantly inherited disease neurofibromatosis type 2 (NF2), which is characterized mainly by vestibular schwannoma carrying a second hit mutation. Complete lack of merlin is also found in spontaneous schwannomas and meningiomas. As the events leading to schwannoma...

Université de Fribourg

Coordination of bowing and fingering in violin playing

Baader, Andreas P. ; Kazennikov, Oleg ; Wiesendanger, Mario

In: Cognitive Brain Research, 2005, vol. 23(2-3), p. 436

Playing string instruments implies motor skills including asymmetrical interlimb coordination. How special is musical skill as compared to other bimanually coordinated, non-musical skillful performances? We succeeded for the first time to measure quantitatively bimanual coordination in violinists playing repeatedly a simple tone sequence. A motion analysis system was used to record finger and bow...