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Université de Fribourg

Postprandial hypotension in older adults: Can it be prevented by drinking water before the meal?

Grobéty, Bastien ; Grasser, Erik Konrad ; Yepuri, Gayathri ; Dulloo, Abdul G. ; Montani, Jean-Pierre

In: Clinical Nutrition, 2015, vol. 34, no. 5, p. 885–891

Background & aimsAn important consequence of ageing is a tendency for postprandial blood pressure to decline, which can lead to fainting. As a possible countermeasure, we investigated in healthy older adults the impact of drinking water before a breakfast meal on postprandial cardiovascular and autonomic functions.MethodsAfter a stable cardiovascular baseline recording for at least 20 min,...

Université de Fribourg

How dieting makes the lean fatter: from a perspective of body composition autoregulation through adipostats and proteinstats awaiting discovery

Dulloo, Abdul G. ; Jacquet, Jean ; Montani, Jean-Pierre ; Schutz, Yves

In: Obesity Reviews, 2015, vol. 16, p. 25–35

Whether dieting makes people fatter has been a subject of considerable controversy over the past 30 years. More recent analysis of several prospective studies suggest, however, that it is dieting to lose weight in people who are in the healthy normal range of body weight, rather than in those who are overweight or obese, that most strongly and consistently predict future weight gain. This paper...

Université de Fribourg

Dieting and weight cycling as risk factors for cardiometabolic diseases: who is really at risk?

Montani, Jean-Pierre ; Schutz, Yves ; Dulloo, Abdul G.

In: Obesity Reviews, 2015, vol. 16, p. 7–18

Despite the poor prognosis of dieting in obesity management, which often results in repeated attempts at weight loss and hence weight cycling, the prevalence of dieting has increased continuously in the past decades in parallel to the steadily increasing prevalence of obesity. However, dieting and weight cycling are not limited to those who are obese or overweight as substantial proportions of...

Université de Fribourg

Cardiovascular and metabolic responses to tap water ingestion in young humans: does the water temperature matter?

Girona, M. ; Grasser, Erik Konrad ; Dulloo, Abdul G. ; Montani, Jean-Pierre

In: Acta Physiologica, 2014, vol. 211, no. 2, p. 358–370

Aim: Drinking water induces short-term cardiovascular and metabolic changes. These effects are considered to be triggered by gastric distension and osmotic factors, but little is known about the influence of water temperature.Methods: We determined, in a randomized crossover study, the acute cardiovascular and metabolic responses to 500 mL of tap water at 3 °C (cold), 22 °C (room) and...

Université de Fribourg

Cardio- and cerebrovascular responses to the energy drink Red Bull in young adults: a randomized cross-over study

Grasser, Erik K. ; Yepuri, Gayathri ; Dulloo, Abdul G. ; Montani, Jean-Pierre

In: European Journal of Nutrition, 2014, p. 1–11

Purpose: Energy drinks are beverages containing vasoactive metabolites, usually a combination of caffeine, taurine, glucuronolactone and sugars. There are concerns about the safety of energy drinks with some countries banning their sales. We determined the acute effects of a popular energy drink, Red Bull, on cardiovascular and hemodynamic variables, cerebrovascular parameters and microvascular...

Université de Fribourg

Sitting comfortably versus lying down: Is there really a difference in energy expenditure?

Miles-Chan, Jennifer Lynn ; Sarafian, Delphine ; Montani, Jean-Pierre ; Schutz, Yves ; Dulloo, Abdul G.

In: Clinical Nutrition, 2014, vol. 33, no. 1, p. 175–178

Background and aims: Energy expenditure (EE) during sitting is widely assumed to be higher than that while lying down, but supporting evidence is equivocal. Despite this, resting EE in the sitting position is often used as a proxy for basal metabolic rate. Here we investigate whether EE differs in the comfortable seated position compared to supine (lying) position.Methods: EE and respiratory...

Université de Fribourg

Energy gap in the aetiology of body weight gain and obesity: a challenging concept with a complex evaluation and pitfalls

Schutz, Yves ; Byrne, N. M. ; Dulloo, Abdul G. ; Hills, A. P.

In: Obesity Facts, 2014, vol. 7, no. 1, p. 15–25

The concept of energy gap(s) is useful for understanding the consequence of a small daily, weekly, or monthly positive energy balance and the inconspicuous shift in weight gain ultimately leading to overweight and obesity. Energy gap is a dynamic concept: an initial positive energy gap incurred via an increase in energy intake (or a decrease in physical activity) is not constant, may fade out...

Université de Fribourg

Comment les régimes amaigrissants font grossir : d’une perspective d’autorégulation de la composition corporelle = How dieting makes some fatter: From a perspective of human body composition autoregulation

Dulloo, Abdul G. ; Jacquet, Jean ; Seydoux, Josiane ; Montani, Jean-Pierre

In: Cahiers de Nutrition et de Diététique, 2013, vol. 48, no. 1, p. 15–25

Le titre d’un livre publié en 1983 ‘Dieting Makes You Fat’ – concrétise la notion que faire un régime pour contrôler son poids, et par conséquent l’effet yo-yo, prédispose l’individu à être encore plus gras. Alors que cette notion est controversée, son débat souligne le fossé qui existe dans notre compréhension des lois fondamentales de la physiologie qui gouvernent la...