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Université de Fribourg

Ectopic fat storage in heart, blood vessels and kidneys in the pathogenesis of cardiovascular diseases

Montani, Jean-Pierre ; Carroll, Joan F. ; Dwyer, Terry M. ; Antic, Vladan ; Yang, Zhihong ; Dulloo, Abdul G.

In: International Journal of Obesity, 2004, vol. 28, p. S58-65

In humans and most animal models, the development of obesity leads not only to increased fat depots in classical adipose tissue locations but also to significant lipid deposits within and around other tissues and organs, a phenomenon known as ectopic fat storage. The purpose of this review is to explore the possible locations of ectopic fat in key target-organs of cardiovascular control (heart,...

Université de Fribourg

The effects of catechin rich teas and caffeine on energy expenditure and fat oxidation: a meta-analysis

Hursel, R. ; Viechtbauer, W. ; Dulloo, Abdul G. ; Tremblay, A. ; Tappy, L. ; Rumpler, W. ; Westerterp-Plantenga, M. S.

In: Obesity Reviews, 2011, vol. 12, no. 7, p. e573–e581

Different outcomes of the effect of catechin-caffeine mixtures and caffeine-only supplementation on energy expenditure and fat oxidation have been reported in short-term studies. Therefore, a meta-analysis was conducted to elucidate whether catechin-caffeine mixtures and caffeine-only supplementation indeed increase thermogenesis and fat oxidation. First, English-language studies measuring daily...

Université de Fribourg

Energy gap in the aetiology of body weight gain and obesity: a challenging concept with a complex evaluation and pitfalls

Schutz, Yves ; Byrne, N. M. ; Dulloo, Abdul G. ; Hills, A. P.

In: Obesity Facts, 2014, vol. 7, no. 1, p. 15–25

The concept of energy gap(s) is useful for understanding the consequence of a small daily, weekly, or monthly positive energy balance and the inconspicuous shift in weight gain ultimately leading to overweight and obesity. Energy gap is a dynamic concept: an initial positive energy gap incurred via an increase in energy intake (or a decrease in physical activity) is not constant, may fade out...

Université de Fribourg

Fructose ingestion acutely elevates blood pressure in healthy young humans

Brown, Clive M. ; Dulloo, Abdul G. ; Yepuri, Gayathri ; Montani, Jean-Pierre

In: American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, 2008, vol. 294, p. R730-R737

Brown, Clive M.; Division of Physiology, Department of Medicine, University of Fribourg, Switzerland Dulloo, Abdul G.; Division of Physiology, Department of Medicine, University of Fribourg, Switzerland Yepuri, Gayathri; Division of Physiology, Department of Medicine, University of Fribourg, Switzerland Montani, and Jean-Pierre; Division of Physiology, Department of Medicine, University of...

Université de Fribourg

How dieting makes the lean fatter: from a perspective of body composition autoregulation through adipostats and proteinstats awaiting discovery

Dulloo, Abdul G. ; Jacquet, Jean ; Montani, Jean-Pierre ; Schutz, Yves

In: Obesity Reviews, 2015, vol. 16, p. 25–35

Whether dieting makes people fatter has been a subject of considerable controversy over the past 30 years. More recent analysis of several prospective studies suggest, however, that it is dieting to lose weight in people who are in the healthy normal range of body weight, rather than in those who are overweight or obese, that most strongly and consistently predict future weight gain. This paper...

Université de Fribourg

How dieting might make some fatter: modeling weight cycling toward obesity from a perspective of body composition autoregulation

Jacquet, Philippe ; Schutz, Yves ; Montani, Jean-Pierre ; Dulloo, Abdul G.

In: International Journal of Obesity, 2020, vol. 44, p. 1243-1253

The notion that dieting makes some people fatter has in the past decade gained considerable interest from both epidemiological predictions and biological plausibility. Several large-scale prospective studies have suggested that dieting to lose weight is associated with future weight gain and obesity, with such predictions being stronger and more consistent among dieters who are in the normal...