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Université de Fribourg

Developmental regulation of expression of schizophrenia susceptibility genes in the primate hippocampal formation

Favre, Guillaume ; Banta Lavenex, Pamela A. ; Lavenex, Pierre

In: Translational Psychiatry, 2012, vol. 2, p. e173

The hippocampal formation is essential for normal memory function and is implicated in many neurodevelopmental, neurodegenerative and neuropsychiatric disorders. In particular, abnormalities in hippocampal structure and function have been identified in schizophrenic subjects. Schizophrenia has a strong polygenic component, but the role of numerous susceptibility genes in normal brain development...

Université de Fribourg

Postnatal development of the amygdala: A stereological study in macaque monkeys

Chareyron, Loïc J. ; Banta Lavenex, Pamela A. ; Amaral, David G. ; Lavenex, Pierre

In: The Journal of Comparative Neurology, 2012, p. -

Abnormal development of the amygdala has been linked to several neurodevelopmental disorders, including schizophrenia and autism. However, the postnatal development of the amygdala is not easily explored at the cellular level in humans. Here, we performed a stereological analysis of the macaque monkey amygdala in order to characterize the cellular changes underlying its normal structural...