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Université de Fribourg

Postnatal development of the hippocampal formation: A stereological study in macaque monkeys

Jabès, Adeline ; Banta Lavenex, Pamela A. ; Amaral, David G. ; Lavenex, Pierre

In: The Journal of Comparative Neurology, 2011, p. -

We performed a stereological analysis of neuron number, neuronal soma size, and volume of individual regions and layers of the macaque monkey hippocampal formation during early postnatal development. We found a protracted period of neuron addition in the dentate gyrus throughout the first postnatal year and a concomitant late maturation of the granule cell population and individual dentate...

Université de Fribourg

Intrinsic connections of the macaque monkey hippocampal formation: II. CA3 connections

Kondo, Hideki ; Lavenex, Pierre ; Amaral, David G.

In: The Journal of Comparative Neurology, 2009, vol. 515, no. 3, p. 349 - 377

We examined the topographic organization of the connections of the CA3 field of the macaque monkey hippocampus. Discrete anterograde and retrograde tracer injections were made at various positions within CA3 and CA1. The projections from CA3 to CA1 (Schaffer collaterals), which terminate in the strata radiatum, pyramidale, and oriens, are present throughout the entire transverse extent of CA1....

Université de Fribourg

Postmortem changes in the neuroanatomical characteristics of the primate brain: Hippocampal formation

Lavenex, Pierre ; Lavenex, Pamela Banta ; Bennett, Jeffrey L. ; Amaral, David G.

In: The Journal of Comparative Neurology, 2009, vol. 512, no. 1, p. 27 - 51

Comparative studies of the structural organization of the brain are fundamental to our understanding of human brain function. However, whereas brains of experimental animals are fixed by perfusion of a fixative through the vasculature, human or ape brains are fixed by immersion after varying postmortem intervals. Although differential treatments might affect the fundamental characteristics of the...