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Centre de Recherches Energétiques et Municipales

La gestion énergétique d’une ville suisse: Martigny

Revaz, Jean-Marc

In: Actes du Colloque international: Villes, Energie et Environnement, 2001, p. 28-36

Université de Fribourg

Angiofil®-mediated visualization of the vascular system by microcomputed tomography: a feasibility study

Grabherr, Silke ; Hess, Andreas ; Karolczak, Marek ; Thali, Michael J. ; Friess, Sebastian D. ; Kalender, Willi A. ; Dirnhofer, Richard ; Djonov, Valentin

In: Microscopy Research and Technique, 2008, vol. 71, no. 7, p. 551 - 556

Visualization of the vascular systems of organs or of small animals is important for an assessment of basic physiological conditions, especially in studies that involve genetically manipulated mice. For a detailed morphological analysis of the vascular tree, it is necessary to demonstrate the system in its entirety. In this study, we present a new lipophilic contrast agent, Angiofil®, for...

Université de Fribourg

Developing swiss paraplegic research: Building a research institution from the comprehensive perspective

Stucki, Gerold ; Reinhardt, Jan D. ; Cieza, Alarcos ; Brach, Mirjam ; Celio, Marco R. ; Joggi, Daniel ; Villiger, Beat ; Zäch, Guido A. ; Krieg, Walter

In: Disability & Rehabilitation, 2008, vol. 30, no. 14, p. 1063 - 1078

Purpose. To illustrate the conceptualization and development of a research institution from the comprehensive perspective based on the integrative model of functioning provided by the World Health Organization's (WHO) International Classification of Functioning, Disability and Health (ICF). The newly founded research institution Swiss Paraplegic Research which focuses on the comprehensive study...

Université de Fribourg

Laparoscopic training on Thiel human cadavers: A model to teach advanced laparoscopic procedures

Frésard, Isabelle ; Häfliger, André ; Bergmann, Mathias ; Krähenbühl, Lukas

In: Surgical Endoscopy, 2008, vol. 22, no. 4, p. 901-906

Background: Nowadays, the laparoscopic approach represents the gold standard for a wide range of various basic and advanced procedures. To reduce the learning curve in advanced laparoscopic surgery, the search for new teaching tools is of utmost importance. Our experiences with a new teaching tool to train advanced laparoscopic procedures are reported. Methods: Hands-on training courses in...

Université de Fribourg

Decreased infarct size after focal cerebral ischemia in mice chronically infected with Toxoplasma gondii

Arsenijevic, Denis ; Bilbao, F. de ; Vallet, Philippe ; Hemphill, Andrew ; Gottstein, B. ; Richard, Denis ; Giannakopoulos, Panteleimon ; Langhans, Wolfgang

In: Neuroscience, 2007, vol. 150, no. 3, p. 537-546

To determine whether Toxoplasma gondii infection could modify biological phenomena associated with brain ischemia, we investigated the effect of permanent middle cerebral artery occlusion (MCAO) on neuronal survival, inflammation and redox state in chronically infected mice. Infected animals showed a 40% to 50% decrease of infarct size compared with non-infected littermates 1, 4 and 14 days after...

Université de Fribourg

The circadian clock and mood-related behavior : addendum to Hampp G. et al., Regulation of monoamine oxidase a by circadian-clock components implies clock influence on mood. Curr Biol 18:678–83, 2008.

Hampp, Gabriele ; Albrecht, Urs

In: Communicative & Integrative Biology, 2008, vol. 1, no. 1, p. 1-3

Over many years evidence accumulated that circadian rhythms are related to psychiatric disorders.1-3 However, a mechanistic relationship between the circadian clock and mood related behaviors remained enigmatic. Now, we have reported that monoamine oxidase A (MAOA), a mitochondrial enzyme degrading catecholamines including dopamine, is regulated by components of the circadian clock .4...

Centre de Recherches Energétiques et Municipales

Enhancing the Quality of Energy Services in Urban Areas by Means of Renewable Energy Technologies and ITC in Energy Networks : Issues, Challenges and Opportunities

Nguene, Gustave ; Cherix, Gaëtan ; Maréchal, François ; Finger, Matthias ; Revaz, Jean-Marc

In: ISESCO Science and Technology Vision, 2007, vol. 3, no. 3, p. 49-53

Les zones urbaines sont caractérisées par une grande concentration d'activités économiques et sociales. La conséquence est que les activités résidentielles, commerciales ou industrielles exigent un énorme taux de consommation de ressources. Cela peut aboutir à des problèmes liés à l'environnement. En plus de l'épuisement des ressources fossiles dans un avenir proche, il y a des...

Università della Svizzera italiana

From context to system and back : how systems emerge from actors cognitive and social interactions : a system dynamics perspective

Colombo, Gianluca ; Mollona, Edoardo

In this paper, the system is viewed as a construction based on the actors’ cognitive and social interactions. The system is the result of multiple – actor sense making (Weick 1995), but at the same time it orients social sense making. In this process each actor’s point of view is a representation of both the system and the context perceived as pertinent by the actor. In other words, the...

Université de Fribourg

Substrate cycling between de novo lipogenesis and lipid oxidation: a thermogenic mechanism against skeletal muscle lipotoxicity and glucolipotoxicity

Dulloo, Abdul G. ; Gubler, Marcel ; Montani, Jean-Pierre ; Seydoux, Josiane ; Solinas, Giovanni

In: International Journal of Obesity, 2004, vol. 28 (Suppl. 4), p. S29-S37

Life is a combustion, but how the major fuel substrates that sustain human life compete and interact with each other for combustion has been at the epicenter of research into the pathogenesis of insulin resistance ever since Randle proposed a 'glucose-fatty acid cycle' in 1963. Since then, several features of a mutual interaction that is characterized by both reciprocality and dependency between...