In: Toxicological Sciences, 2014, vol. 137, no. 1, p. 55-64
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In: European Journal of Nanomedicine, 2014, vol. 6, no. 4, p. 201-215
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In: MRS Bulletin, 2014, vol. 39, no. 11, p. 984-989
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In: BioNanoMaterials, 2013, vol. 14, no. 3-4, p. 239-248
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In: Cardiovascular Research, 2012, vol. 94, no. 1, p. 58-65
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In: ACS Applied Materials & Interfaces, 2017, vol. 9, no. 22, p. 18501–18511
A major hurdle in the development of biomedical nanoparticles (NP) is understanding how they interact with complex biological systems and navigate biological barriers to arrive at pathological targets. It is becoming increasingly evident that merely controlling particle physicochemical properties may not be sufficient to mediate particle biodistribution in dynamic environments. Thus,...
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In: Nanomedicine, 2017, vol. 12, no. 10, p. 1095–1099
As the range of engineered nanoparticles (NPs) designed as specific carriers increases, for example for cell targeting and drug delivery, the question on how many NPs are interacting or are taken up by cells is becoming increasingly important for any potential biomedical application. On one hand, the delivered dose of such NPs to the targeted cells is a key parameter in the assessment of...
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In: ACS Nano, 2017, p. -
Although acute pulmonary toxicity of carbon nanotubes (CNTs) has been extensively investigated, the knowledge of potential health effects following chronic occupational exposure is currently limited and based only upon in vivo approaches. Our aim was to realistically mimic subchronic inhalation of multiwalled CNTs (MWCNTs) in vitro, using the air–liquid interface cell exposure (ALICE)...
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In: Journal of Magnetism and Magnetic Materials, 2017, vol. 427, p. 212–219
Magnetic thermo-responsive hydrogels are a new class of materials that have recently attracted interest in biomedicine due to their ability to change phase upon magnetic stimulation. They have been used for drug release, magnetic hyperthermia treatment, and can potentially be engineered as stimuli-responsive substrates for cell mechanobiology. In this regard, we propose a series of magnetic...
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In: Scientific Reports, 2017, vol. 7, no. 1, p. 434
Determination of the cell type specific response is essential towards understanding the cellular mechanisms associated with disease states as well as assessing cell-based targeting of effective therapeutic agents. Recently, there have been increased calls for advanced in vitro multi-cellular models that provide reliable and valuable tools correlative to in vivo. In this pursuit the ability to...
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