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Università della Svizzera italiana

An experimental comparison of a space-time multigrid method with PFASST for a reaction-diffusion problem

Benedusi, Pietro ; Minion, Michael L. ; Krause, Rolf

In: Computers and mathematics with applications, 2021, vol. 99, p. 162-170

We consider two parallel-in-time approaches applied to a (reaction) diffusion problem, possibly non-linear. In particular, we consider PFASST (Parallel Full Approximation Scheme in Space and Time) and space-time multigrid strategies. For both approaches, we start from an integral formulation of the continuous time dependent problem. Then, a collocation form for PFASST and a discontinuous ...

Università della Svizzera italiana

VerifyThis 2019 : a program verification competition

Dross, Claire ; Furia, Carlo A ; Huisman, Marieke ; Monahan, Rosemary ; Müller, Peter

In: International Journal on Software Tools for Technology Transfer, 2021, vol. 23, p. 883–893

VerifyThis is a series of program verification competitions that emphasize the human aspect: participants tackle the verification of detailed behavioral properties—something that lies beyond the capabilities of fully automatic verification and requires instead human expertise to suitably encode programs, specifications, and invariants. This paper describes the 8th edition of VerifyThis, ...

Università della Svizzera italiana

Dati evidence-based sulla affidabilità dei sistemi ecografici per la stratificazione del rischio di malignità del nodulo tiroideo (TIRADS)

Trimboli, Pierpaolo ; Scappaticcio, Lorenzo ; Castellana, Marco

In: L'endocrinologo, 2021, vol. 22, no. 3, p. 225–230

L’esame strumentale più comunemente utilizzato per valutare il rischio di malignità del nodulo tiroideo è l’ecografia. Con questo esame è possibile individuare posizione, dimensioni e caratteristiche del nodulo. Dal momento che l’uso dei singoli aspetti ecografici di sospetto ha dimostrato una bassa riproducibilità nell’indicazione all’agoaspirato, nel corso degli ultimi anni...

Università della Svizzera italiana

Prevalence of physiological uptake in the pancreas on somatostatin receptor-based PET/CT : a systematic review and a meta-analysis

Boughdad, Sarah ; Meyer, Marie ; Prior, John O. ; Fernandes, Victor ; Allenbach, Gilles ; Kamani, Christel ; Jreige, Mario ; Albano, Domenico ; Bertagna, Francesco ; Nicod-Lalonde, Marie ; Schaefer, Niklaus ; Treglia, Giorgio

In: Clinical and Translational Imaging, 2021, vol. 9, no. 4, p. 353–360

Background: Physiological focal radiopharmaceutical uptake in the head and uncinate process of the pancreas may be seen on somatostatin receptor-based PET/CT and might lead to false-positive results for neuroendocrine tumours (NETs). We aimed to perform a systematic review and a meta-analysis about the prevalence of this finding. Methods: We performed a comprehensive computer literature search...

Università della Svizzera italiana

Thyroid sequelae of COVID-19 : a systematic review of reviews

Trimboli, Pierpaolo ; Camponovo, Chiara ; Scappaticcio, Lorenzo ; Bellastella, Giuseppe ; Piccardo, Arnoldo ; Rotondi, Mario

In: Reviews in Endocrine and Metabolic Disorders, 2021, vol. 22, no. 2, p. 485-491

The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the potential to cause multi- organ effects including endocrine disorders. The impact of COVID-19 on the thyroid gland has been described but several aspects have to be clarified. The systematic review was conceived to achieve more solid information about: 1) which thyroid...

Università della Svizzera italiana

Intestinal microbiota drives cholestasis-induced specific hepatic gene expression patterns

Juanola, Oriol ; Hassan, Mohsin ; Kumar, Pavitra ; Yilmaz, Bahtiyar ; Keller, Irene ; Simillion, Cédric ; Engelmann, Cornelius ; Tacke, Frank ; Dufour, Jean-François ; De Gottardi, Andrea ; Moghadamrad, Sheida

In: Gut microbes, 2021, vol. 13, no. 1, p. 20

Intestinal microbiota regulates multiple host metabolic and immunological processes. Consequently, any difference in its qualitative and quantitative composition is susceptible to exert significant effects, in particular along the gut-liver axis. Indeed, recent findings suggest that such changes modulate the severity and the evolution of a wide spectrum of hepatobiliary disorders. However, the...

Università della Svizzera italiana

Magnesium metabolism in chronic alcohol-use disorder : meta-analysis and systematic review

Vanoni, Flora O. ; Milani, Gregorio P. ; Agostoni, Carlo ; Treglia, Giorgio ; Faré, Pietro B. ; Camozzi, Pietro ; Lava, Sebastiano A. G. ; Bianchetti, Mario G. ; Janett, Simone

In: Nutrients, 2021, vol. 13, no. 6, p. 11

Chronic alcohol-use disorder has been imputed as a possible cause of dietary magnesium depletion. The purpose of this study was to assess the prevalence of hypomagnesemia in chronic alcohol-use disorder, and to provide information on intracellular magnesium and on its renal handling. We carried out a structured literature search up to November 2020, which returned 2719 potentially relevant...

Università della Svizzera italiana

The ABC of Deutsch–Hayden descriptors

Bédard, Charles Alexandre

In: Quantum reports, 2021, vol. 3, no. 2, p. 272-285

It has been more than 20 years since Deutsch and Hayden proved the locality of quantum theory, using the Heisenberg picture of quantum computational networks. Of course, locality holds even in the face of entanglement and Bell’s theorem. Today, most researchers in quantum foundations are still convinced not only that a local description of quantum systems has not yet been provided, but that...

Università della Svizzera italiana

Vitamin D status in adolescents during COVID-19 pandemic : a cross-sectional comparative study

Meoli, Martina ; Muggli, Franco ; Lava, Sebastiano A. G. ; Bianchetti, Mario G. ; Agostoni, Carlo ; Kocher, Claudine ; Bührer, Thomas W. ; Ciliberti, Letizia ; Simonetti, Giacomo D. ; Milani, Gregorio P.

In: Nutrients, 2021, vol. 13, no. 5, p. 7

Vitamin D has been claimed to be effective in the response to infections, including the respiratory syndrome coronavirus 2 (SARS-CoV-2). It is supposed that lockdown measures and fear of SARS-CoV-2 infection might reduce vitamin D levels through the modification of lifestyle. However, very few data exist on the association between lockdown measures and vitamin D status in humans. For this...

Università della Svizzera italiana

Fibrin sealants and axillary lymphatic morbidity : a systematic review and meta-analysis of 23 clinical randomized trials

Gasparri, Maria Luisa ; Kuehn, Thorsten ; Ruscito, Ilary ; Zuber, Veronica ; Di Micco, Rosa ; Galiano, Ilaria ; Navarro Quinones, Siobana C. ; Santurro, Letizia ; Di Vittorio, Francesca ; Meani, Francesco ; Bassi, Valerio ; Ditsch, Nina ; Mueller, Michael D. ; Bellati, Filippo ; Caserta, Donatella ; Papadia, Andrea ; Gentilini, Oreste D.

In: Cancers, 2021, vol. 13, no. 9, p. 15

Axillary dissection is a highly mobile procedure with severe lymphatic consequences. The off-label application of fibrin sealants in the axilla, with the sole aim to eliminate dead space and to provoke sealing of the disrupted lymphatic vessels at the end of axillary dissection, is an experimental procedure to reduce lymphatic morbidity. The aim of our systematic review and meta-analysis is to ...