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Università della Svizzera italiana

Extreme sleep state misperception : from psychopathology to objective-subjective sleep measures

Castelnovo, Anna ; Ferri, Raffaele ; Galbiati, Andrea ; Rossi, Alessandro ; Zucconi, Marco ; Castronovo, Vincenza ; Strambi, Luigi-Ferini ; Manconi, Mauro

In: International journal of psychophysiology, 2021, vol. 167, p. 77-85

Study objectives: We tested the hypothesis that patients with extreme sleep state misperception display higher levels of psychopathology and reduced quantitative estimation abilities compared to other patients with insomnia. Secondary aims included the evaluation of group differences in subjective self-reported quality of life and sleep quality and objective sleep parameters. Methods: In this...

Università della Svizzera italiana

Space–time shape uncertainties in the forward and inverse problem of electrocardiography

Gander, Lia ; Krause, Rolf ; Multerer, Michael ; Pezzuto, Simone

In: International journal for numerical methods in biomedical engineering, 2021, vol. 37, no. 10, p. 23

In electrocardiography, the “classic” inverse problem is the reconstruction of electric potentials at a surface enclosing the heart from remote recordings at the body surface and an accurate description of the anatomy. The latter being affected by noise and obtained with limited resolution due to clinical constraints, a possibly large uncertainty may be perpetuated in the inverse ...

Università della Svizzera italiana

Head-to-head comparison of FNA cytology vs. calcitonin measurement in FNA washout fluids (FNA-CT) to diagnose medullary thyroid carcinoma : A systematic review and meta-analysis

Trimboli, Pierpaolo ; Giannelli, Jacopo ; Marques, Bernardo ; Piccardo, Arnoldo ; Crescenzi, Anna ; Deandrea, Maurilio

In: Endocrine, 2022, no. 75, p. 33–39

Purpose: The sensitivity of cytology after fine needle aspiration (FNA-cytology) in detecting medullary thyroid carcinoma (MTC) is low. To overcome this problem, measuring calcitonin (CT) in washout fluid of FNA (FNA-CT) has been largely diffused and showed good performance. However, no evidence-based study exists comparing systematically the sensitivity of FNA-cytology and FNA-CT. This study...

Università della Svizzera italiana

Neuroticism and internet addiction : What is next? A systematic conceptual review

Marciano, Laura ; Camerini, Anne-Linda ; Schulz, Peter J.

In: Personality and individual differences, 2022, vol. 185, p. 10

The personality trait of neuroticism (N) has consistently shown to be a risk factor for Internet Addiction (IA). Review literature, however, looked at this in bivariate analyses only. To the best of our knowledge, we conducted the first review that systematically and conceptually summarized results based on the inclusion of additional factors, thus coming closer to the complex nature of the ...

Università della Svizzera italiana

Maternal psychological distress and children’s internalizing/externalizing problems during the COVID-19 pandemic : the moderating role played by hypermentalization

Bianco, Federica ; Levante, Annalisa ; Petrocchi, Serena ; Lecciso, Flavia ; Castelli, Ilaria

In: International journal of environmental research and public health, 2021, vol. 18, no. 19, p. 17

In order to explore the psychological impact of the COVID‐19 outbreak on the caregiver–child relationship, we investigated the interplay among COVID‐19 exposure and children’s internalizing/externalizing problems during the Italian lockdown, hypothesizing a mediation effect played by maternal distress. Additionally, we included maternal reflective functioning (i.e., hypermentalization)...

Università della Svizzera italiana

Artificial intelligence in thyroid field : a comprehensive review

Bini, Fabiano ; Pica, Andrada ; Azzimonti, Laura ; Giusti, Alessandro ; Ruinelli, Lorenzo ; Marinozzi, Franco ; Trimboli, Pierpaolo

In: Cancers, 2021, vol. 13, no. 19, p. 18

Artificial intelligence (AI) uses mathematical algorithms to perform tasks that require human cognitive abilities. AI-based methodologies, e.g., machine learning and deep learning, as well as the recently developed research field of radiomics have noticeable potential to transform medical diagnostics. AI-based techniques applied to medical imaging allow to detect biological abnormalities, to...

Università della Svizzera italiana

Does health literacy reinforce disease knowledge gain? : a prospective observational study of hungarian COPD patients

Papp-Zipernovszky, Orsolya ; Csabai, Márta ; Schulz, Peter J. ; Varga, János T.

In: Journal of clinical medicine, 2021, vol. 10, no. 17, p. 13

We set out to measure the health literacy (HL) of COPD patients using the Short Test of Functional Health Literacy (S- TOFHLA), perception-based screening questions (BHLS), and a specific disease knowledge test (COPD-Q). Our main focus is the relationship between functional HL and patients’ disease-knowledge, which contributes to the clarification of the relationship between the different...

Università della Svizzera italiana

Autoimmmune hepatitis

Terziroli Beretta-Piccoli, Benedetta ; Mieli Vergani, Giorgina ; Vergani, Diego

In: Cellular & molecular immunology, 2021, p. 19

Autoimmune hepatitis (AIH) is a T-cell mediated, inflammatory liver disease affecting all ages and characterized by female preponderance, elevated serum transaminase and immunoglobulin G levels, positive circulating autoantibodies, and presence of interface hepatitis at liver histology. AIH type 1, affecting both adults and children, is defined by positive anti- nuclear and/or antismooth muscle...

Università della Svizzera italiana

Autoimmune hepatitis : serum autoantibodies in clinical practice

Terziroli Beretta-Piccoli, Benedetta ; Mieli Vergani, Giorgina ; Vergani, Diego

In: Clinical reviews in allergy & immunology, 2021, p. 14

Circulating autoantibodies are a key diagnostic tool in autoimmune hepatitis (AIH), being positive in 95% of the cases if tested according to dedicated guidelines issued by the International Autoimmune Hepatitis Group. They also allow the distinction between type 1 AIH, characterized by positive anti-nuclear and/or anti-smooth muscle antibody, and type 2 AIH, characterized by positive...

Università della Svizzera italiana

Posterior reversible leukoencephalopathy syndrome associated with acute postinfectious glomerulonephritis : systematic review

Orlando, Corinne ; Milani, Gregorio P. ; Simonetti, Giacomo D. ; Goeggel Simonetti, Barbara ; Lava, Sebastiano A. G. ; Wyttenbach, Rolf ; Bianchetti, Mario G. ; Cristallo Lacalamita, Marirosa

In: Pediatric nephrology, 2021, p. 9

Background Kidney diseases are a recognized cause of posterior reversible leukoencephalopathy syndrome, usually abbreviated as PRES. The purpose of this review was to systematically address the association between acute postinfectious glomerulonephritis and PRES. Methods We performed a systematic review of the literature on acute postinfectious glomerulonephritis associated with PRES. The...