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Université de Fribourg

Comparison of a novel biodegradable polymer sirolimus-eluting stent With a durable polymer everolimus-eluting stent results of the randomized BIOFLOW-II trial

Windecker, Stephan ; Haude, Michael ; Neumann, Franz-Josef ; Stangl, karl ; Witzenbichler, Bernhard ; Slagboom, Ton ; Sabaté, Manel ; Goicolea, Javier ; Barragan, Paul ; Cook, Stéphane ; Piot, Christophe ; Richardt, Gert ; Merkely, Béla ; Schneider, Henrik ; Bilger, Johannes ; Erne, Paul ; Waksman, Ron ; Zaugg, Serge ; Jüni, Peter ; Lefèvre, Thierry

In: Circulation: Cardiovascular Interventions, 2015, vol. 8, no. 2, p. e001441

Background—Biodegradable polymers for release of antiproliferative drugs from drug-eluting stents aim to improve vascular healing. We assessed noninferiority of a novel ultrathin strut drug-eluting stent releasing sirolimus from a biodegradable polymer (Orsiro, O-SES) compared with the durable polymer Xience Prime everolimus-eluting stent (X-EES) in terms of the primary end...

Université de Fribourg

Impact of incomplete stent apposition on long-term clinical outcome after drug-eluting stent implantation

Vogel, Rolf ; Seiler, Christian ; Eberli, Franz R. ; Lüscher, Thomas ; Meier, Bernhard ; Jüni, Peter ; Windecker, Stephan

In: European Heart Journal, 2012, vol. 33, no. 11, p. 1334-1343

Aims Late acquired incomplete stent apposition (ISA) is more common after drug-eluting stent (DES) than bare metal stent (BMS) implantation and has been associated with vascular hypersensitivity and stent thrombosis (ST). We investigated the impact of incidentally discovered ISA as assessed by intravascular ultrasound (IVUS) 8 months after DES implantation on the long-term clinical...

Université de Fribourg

Balloon angioplasty using the "grip" scoring balloon for treatment of coronary in-stent restenosis - immediate and 12-month clinical outcomes

Puricel, Serban ; Schoepke, Linus ; Togni, Mario ; Oberhänsli, Markus ; Moschovitis, Aris ; Meier, Bernhard ; Windecker, Stephan ; Cook, Stéphane

In: Cardiovascular Medicine, 2012, vol. 15, no. 12, p. 354–361

Objectives: We sought to determine the efficacy and safety of a scoring balloon for the treatment of in-stent restenosis (ISR). Background: The optimal therapy for ISR is not yet properly established and subject to many discussions. The GRIP™ Balloon (Acrostak, Switzerland) might be of interest for the treatment of certain types of ISR. Methods: Between 2003 and 2009, 157 patients who were...

Université de Fribourg

Comparison of Titanium-Nitride-Oxide–Coated stents with Zotarolimus-Eluting stents for coronary revascularization: a randomized controlled trial

Pilgrim, Thomas ; Räber, Lorenz ; Limacher, Andreas ; Löffel, Lukas ; Wenaweser, Peter ; Cook, Stéphane ; Stauffer, Jean-Christophe ; Togni, Mario ; Vogel, Rolf ; Garachemani, Ali ; Moschovitis, Aris ; Khattab, Ahmed A. ; Seiler, Christian ; Meier, Bernhard ; Jüni, Peter ; Windecker, Stephan

In: Journal of the American College of Cardiology: Cardiovascular Interventions, 2011, vol. 4, no. 6, p. 672-682

Objectives: This study sought to compare the efficacy of passive stent coating with titanium-nitride-oxide (TiNO) with drug-eluting stents releasing zotarolimus (ZES) (Endeavor, Medtronic, Minneapolis, Minnesota).Background: Stent coating with TiNO has been shown to reduce restenosis compared with bare-metal stents in experimental and clinical studies.Methods: In an assessor-blind noninferiority...