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Consortium of Swiss Academic Libraries

Amoebal pathogens as emerging causal agents of pneumonia

Lamoth, Frédéric ; Greub, Gilbert

In: FEMS Microbiology Reviews, 2010, vol. 34, no. 3, p. 260-280

Consortium of Swiss Academic Libraries

HIV Lipoatrophy and Mosquito Bites

Greub, Gilbert ; Fellay, Jacques ; Telenti, Amalio

In: Clinical Infectious Diseases, 2002, vol. 34, no. 2, p. 288-289

Université de Fribourg

Β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue

Somm, Emmanuel ; Henry, Hugues ; Bruce, Stephen J. ; Aeby, Sébastien ; Rosikiewicz, Marta ; Sykiotis, Gerasimos P. ; Asrih, Mohammed ; Jornayvaz, François R. ; Denechaud, Pierre Damien ; Albrecht, Urs ; Mohammadi, Moosa ; Dwyer, Andrew ; Jr., James S. Acierno ; Schoonjans, Kristina ; Fajas, Lluis ; Greub, Gilbert ; Pitteloud, Nelly

In: JCI Insight, 2017, vol. 2, no. 8, p. -

β-Klotho (encoded by Klb) is the obligate coreceptor mediating FGF21 and FGF15/19 signaling. Klb–/– mice are refractory to beneficial action of pharmacological FGF21 treatment including stimulation of glucose utilization and thermogenesis. Here, we investigated the energy homeostasis in Klb–/– mice on high-fat diet in order to better understand the consequences of abrogating both...

Université de Fribourg

Screening of plasmid-mediated MCR-1 colistin-resistance from bacteremia

Nordmann, Patrice ; Assouvie, L. ; Prod’Hom, G. ; Poirel, Laurent ; Greub, Gilbert

In: European Journal of Clinical Microbiology & Infectious Diseases, 2016, vol. 35, no. 11, p. 1891–1892

Université de Fribourg

The salivary microbiome for differentiating individuals: proof of principle

Leake, Sarah L. ; Pagni, Marco ; Falquet, Laurent ; Taroni, Franco ; Greub, Gilbert

In: Microbes and Infection, 2016, vol. 18, no. 6, p. 399–405

Human identification has played a prominent role in forensic science for the past two decades. Identification based on unique genetic traits is driving the field. However, this may have limitations, for instance, for twins. Moreover, high-throughput sequencing techniques are now available and may provide a high amount of data likely useful in forensic science.This study investigates the...

Université de Fribourg

Sequencing and characterizing the genome of Estrella lausannensis as an undergraduate project: training students and biological insights

Bertelli, Claire ; Aeby, Sébastien ; Chassot, Bérénice ; Clulow, James ; Hilfiker, Olivier ; Rappo, Samuel ; Ritzmann, Sébastien ; Schumacher, Paolo ; Terrettaz, Céline ; Benaglio, Paola ; Falquet, Laurent ; Farinelli, Laurent ; Gharib, Walid H. ; Goesmann, Alexander ; Harshman, Keith ; Linke, Burkhard ; Miyazaki, Ryo ; Rivolta, Carlo ; Robinson-Rechavi, Marc ; Meer, Jan Roelof van der ; Greub, Gilbert

In: Frontiers in Microbiology, 2015, vol. 6, p. 101

With the widespread availability of high-throughput sequencing technologies, sequencing projects have become pervasive in the molecular life sciences. The huge bulk of data generated daily must be analyzed further by biologists with skills in bioinformatics and by “embedded bioinformaticians,” i.e., bioinformaticians integrated in wet lab research groups. Thus, students interested in...

Université de Fribourg

Comparative genome analysis of Pseudomonas knackmussii B13, the first bacterium known to degrade chloroaromatic compounds

Miyazaki, Ryo ; Bertelli, Claire ; Benaglio, Paola ; Canton, Jonas ; Coi, Nicoló De ; Gharib, Walid H. ; Gjoksi, Bebeka ; Goesmann, Alexander ; Greub, Gilbert ; Harshman, Keith ; Linke, Burkhard ; Mikulic, Josip ; Mueller, Linda ; Nicolas, Damien ; Robinson-Rechavi, Marc ; Rivolta, Carlo ; Roggo, Clémence ; Roy, Shantanu ; Sentchilo, Vladimir ; Siebenthal, Alexandra Von ; Falquet, Laurent ; Meer, Jan Roelof van der

In: Environmental Microbiology, 2014, p. -

Pseudomonas knackmussii B13 was the first strain to be isolated in 1974 that could degrade chlorinated aromatic hydrocarbons. This discovery was the prologue for subsequent characterization of numerous bacterial metabolic pathways, for genetic and biochemical studies, and which spurred ideas for pollutant bioremediation. In this study, we determined the complete genome sequence of B13 using...

Université de Fribourg

Early expression of the type III secretion system of Parachlamydia acanthamoebae during a replicative cycle within its natural host cell Acanthamoeba castellanii

Croxatto, Antony ; Murset, Valérie ; Chassot, Bérénice ; Greub, Gilbert

In: Pathogens and Disease, 2013, p. –

The type three secretion system (T3SS) operons of Chlamydiales bacteria are distributed in different clusters along their chromosomes and are conserved at both the level of sequence and genetic organization. A complete characterization of the temporal expression of multiple T3SS components at the transcriptional and protein levels has been performed in Parachlamydia acanthamoebae, replicating in...