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MCR-2-mediated plasmid-borne polymyxin resistance most likely originates from Moraxella pluranimalium

Poirel, Laurent ; Kieffer, Nicolas ; Fernandez-Garayzabal, José F. ; Vela, Ana Isabel ; Larpin, Yu ; Nordmann, Patrice

In: Journal of Antimicrobial Chemotherapy, 2017, vol. 72, no. 10, p. 2947-2949

Rapid polymyxin NP test for the detection of polymyxin resistance mediated by the MCR-1/MCR-2 genes

Poirel, Laurent ; Larpin, Yu ; Dobias, Jan ; Stephan, Roger ; Decousser, Jean-Winoc ; Madec, Jean-Yves ; Nordmann, Patrice

In: Diagnostic Microbiology and Infectious Disease, 2018, vol. 90, no. 1, p. 7–10

The Rapid Polymyxin NP test has been recently developed to rapidly detect polymyxin resistance in Enterobacteriaceae. Here we evaluated this test for detecting MCR- 1/MCR-2-producing Enterobacteriaceae using a collection of 70 non-redundant strains either recovered from the environment, animals, or humans. Sensitivity and specificity were found to be 100%.