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    2 results 1
    Université de Fribourg

    Resistance to colistin associated with a single amino acid change in protein PmrB among Klebsiella pneumoniae isolates of worldwide Origin

    Jayol, Aurélie ; Poirel, Laurent ; Brink, Adrian ; Villegas, Maria-Virginia ; Yilmaz, Mesut ; Nordmann, Patrice

    In: Antimicrobial Agents and Chemotherapy, 2014, vol. 58, no. 8, p. 4762–4766

    A series of colistin-resistant Klebsiella pneumoniae isolates recovered from different countries was investigated in order to evaluate the involvement of the PmrA/PmrB two-component system in this resistance. Six isolates possessed a mutated PmrB protein, which is encoded by the pmrB gene, part of the pmrCAB operon involved in lipopolysaccharide modification. The same amino acid substitution...

    Université de Fribourg

    Spread of NDM-1-producing Enterobacteriaceae in a neonatal intensive care unit in Istanbul, Turkey

    Poirel, Laurent ; Yilmaz, Mesut ; Istanbullu, Ayse ; Arslan, Ferhat ; Mert, Ali ; Bernabeu, Sandrine ; Nordmann, Patrice

    In: Antimicrobial Agents and Chemotherapy, 2014, vol. 58, no. 5, p. 2929–2933

    Twenty-two consecutive carbapenem-resistant enterobacterial isolates were recovered from patients hospitalized between January and April 2013 in different units at a university hospital in Istanbul, Turkey. These were Klebsiella pneumoniae isolates producing the carbapenemases OXA-48, NDM-1, and KPC-2, Enterobacter cloacae isolates producing NDM-1, and Escherichia coli isolates producing OXA-48....

    2 results 1