Université de Neuchâtel

Titration-on-a-chip, chemical sensor–actuator systems from idea to commercial product

van der Schoot, Bart ; van der Wal, Peter ; de Rooij, Nicolaas F. ; West, Steve

In: Sensors and Actuators B: Chemical, 2005, vol. 105, no. 1, p. 88-95

The earliest reports of integrated chemical sensor–actuator devices to perform coulometric acid–base titrations date back almost 20 years. Recently a first commercial instrument appeared that allows to perform very rapid, accurate acid–base determinations with a solid-state probe and no need for liquid titrants. This paper reviews some of the early developments and shows the effort that has...