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Consortium of Swiss Academic Libraries

Effect of particle agglomeration in nanotoxicology

Bruinink, Arie ; Wang, Jing ; Wick, Peter

In: Archives of Toxicology, 2015, vol. 89, no. 5, p. 659-675

Université de Fribourg

New approach for time-resolved and dynamic investigations on nanoparticles agglomeration

Anaraki, Neda Iranpour ; Sadeghpour, Amin ; Iranshahi, Kamran ; Toncelli, Claudio ; Cendrowska, Urszula ; Stellacci, Francesco ; Dommann, Alex ; Wick, Peter ; Neels, Antonia

In: Nano Research, 2020, vol. 13, no. 10, p. 2847–2856

Nanoparticle (NP) colloidal stability plays a crucial role in biomedical application not only for human and environmental safety but also for NP efficiency and functionality. NP agglomeration is considered as a possible process in monodispersed NP colloidal solutions, which drastically affects colloidal stability. This process is triggered by changes in the physicochemical properties of the...

Université de Fribourg

Single exposure to aerosolized graphene oxide and graphene nanoplatelets did not initiate an acute biological response in a 3D human lung model

Drasler, Barbara ; Kucki, Melanie ; Delhaes, Flavien ; Buerki-Thurnherr, Tina ; Vanhecke, Dimitri ; Korejwo, Daria ; Chortare, Savvina ; Barosova, Hana ; Hirsch, Cordula ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara ; Wick, Peter

In: Carbon, 2018, vol. 137, p. 125–135

The increased mass production of graphene related materials (GRM), intended for a broad spectrum of applications, demands a thorough assessment of their potential hazard to humans and the environment. Particularly, the paramount concern has been expressed in regard to their interaction with the respiratory system in occupational exposure settings. It has been shown that GRM are easily...

Consortium of Swiss Academic Libraries

Single walled carbon nanotubes (SWCNT) affect cell physiology and cell architecture

Kaiser, Jean-Pierre ; Wick, Peter ; Manser, Pius ; Spohn, Philipp ; Bruinink, Arie

In: Journal of Materials Science: Materials in Medicine, 2008, vol. 19, no. 4, p. 1523-1527

Université de Fribourg

Human asthmatic bronchial cells are more susceptible to subchronic repeated exposures of aerosolized carbon nanotubes at occupationally relevant doses than healthy cells

Chortarea, Savvina ; Barosova, Hana ; Clift, Martin James David ; Wick, Peter ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: ACS Nano, 2017, p. -

Although acute pulmonary toxicity of carbon nanotubes (CNTs) has been extensively investigated, the knowledge of potential health effects following chronic occupational exposure is currently limited and based only upon in vivo approaches. Our aim was to realistically mimic subchronic inhalation of multiwalled CNTs (MWCNTs) in vitro, using the air–liquid interface cell exposure (ALICE)...