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    Université de Fribourg

    Silver(I) complexes with 4,7-phenanthroline efficient in rescuing the zebrafish embryos of lethal Candida albicans infection

    Pavic, Aleksandar ; Savić, Nada D. ; Glišić, Biljana Đ. ; Crochet, Aurélien ; Vojnovic, Sandra ; Kurutos, Atanas ; Stanković, Dalibor M. ; Fromm, Katharina M. ; Nikodinovic-Runic, Jasmina ; Djuran, Miloš I.

    In: Journal of Inorganic Biochemistry, 2019, vol. 195, p. 149–163

    Five novel silver(I) complexes with 4,7-phenanthroline (4,7-phen), [Ag(NO3-O)(4,7- phen-μ-N4,N7)]n (1), [Ag(ClO4-О)(4,7-phen-μ-N4,N7)]n (2), [Ag(CF3COO-O)(4,7- phen-μ-N4,N7)]n (3), [Ag2(H2O)0.58(4,7-phen)3](SbF6)2 (4) and {[Ag2(H2O)(4,7- phen-μ-N4,N7)2](BF4)2}n (5) were synthesized, structurally elucidated and biologically evaluated. These complexes showed selectivity towards Candida spp....