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    Université de Fribourg

    Synthesis and applications of nanocontainers and nanorattles

    Abram, Sarah-Luise ; Yep, Philippe ; Fromm, Katharina M.

    In: CHIMIA International Journal for Chemistry, 2019, vol. 73, no. 1, p. 12–16

    Nanorattles and hollow nanocontainers have unique properties related to the presence of a void space inside the shell, which has been shown to improve the properties of materials for e.g. catalysis, drug release, sensor materials or lithium ion batteries. This article summarizes our recent progress in the synthesis of hollow silica, titania and ceria nanorattles and nanocontainers, eventually...

    Université de Fribourg

    Ag Nanoencapsulation for Antimicrobial Applications

    Abram, Sarah-Luise ; Gagnon, Jacinthe ; Priebe, Magdalena ; Hérault, Nelly ; Fromm, Katharina M.

    In: CHIMIA International Journal for Chemistry, 2018, vol. 72, no. 4, p. 249–252

    Biomaterial-related infections remain a significant challenge in medicine. Antimicrobial materials on the basis of Ag nanoparticles represent a promising solution for this issue. Therefore several Ag-containing nanocontainers and nanorattles have been synthesized and characterized that exhibit remarkable control over the release of Ag+ as antimicrobial active species. Their biological...

    Université de Fribourg

    Antimicrobial silver-filled silica nanorattles with low immunotoxicity in dendritic cells

    Priebe, Magdalena ; Widmer, Jérôme ; Löwa, Nina Suhartha ; Abram, Sarah-Luise ; Mottas, Inès ; Woischnig, Anne-Kathrin ; Brunetto, Priscilla S. ; Khanna, Nina ; Bourquin, Carole ; Fromm, Katharina M.

    In: Nanomedicine: Nanotechnology, Biology and Medicine, 2017, vol. 13, no. 1, p. 11–22

    The progression in the use of orthopedic implants has led to an increase in the absolute number of implant infections, triggering a search for more effective antibacterial coatings. Nanorattles have recently gained interest in biomedical applications such as drug delivery, as encapsulation of the cargo inside the hollow structure provides a physical protection from the surrounding...