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Role of vitamin D in postmenopausal bone health : English Version = Vitamin D und postmenopausale Knochengesundheit : Englische Version

Bischoff-Ferrari, H.

In: Der Gynäkologe, 2015, vol. 48, p. 1-6

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    Titel
    • Role of vitamin D in postmenopausal bone health
      English Version
    Titel Übersetzung ()
    • Vitamin D und postmenopausale Knochengesundheit
    Autor
    • Bischoff-Ferrari, H.. Klinik für Geriatrie, Universitätsspital Zürich, Lehrstuhl Geriatrie und Altersforschung, Rämistrasse100, 8091, Zürich, Schweiz
    Dokumententyp
    • Postprint
    OAI-PMH-ID
    • oai:doc.rero.ch:331197
    Summary
    Fractures contribute significantly to morbidity and mortality of postmenopausal women. Among postmenopausal women aged 60years and older, the mortality-adjusted residual lifetime risk of fracture has been estimated to be 44-65 %. Thus, effective strategies are urgently needed to prevent fractures among postmenopausal women. This review summarizes the available evidence that supports vitamin D3 supplementation at a dose of 800IU per day as a strategy to reduce falls and fractures, including hip fractures, among postmenopausal women by about 20-30 %. This recommendation is supported by the Position Statement on Vitamin D of the International Osteoporosis Foundation, the 2011 World Osteoporosis Day Report, and the US Endocrine Society. Further, this recommendation is supported by the high prevalence of vitamin D deficiency among postmenopausal women. The prevalence of vitamin D deficiency (serum levels below 50nmol/l or 20ng/ml) among younger and older postmenopausal women has been found to be about 50 % in many countries around the world, with the highest prevalence (80 %) in older women with hip fractures.