Faculté des sciences et de médecine

Supramolecular structures in lipid digestion and implications for functional food delivery

Salentinig, Stefan

In: Current Opinion in Colloid & Interface Science, 2019, vol. 39, p. 190–201

The daily diet is important for our survival, health, and wellbeing. Functional food materials, which tailor the digestion process, can help maintaining and even improving human health and lifestyle. Knowledge on how food products, particularly food emulsions such as milk, interact with the digestive system, where they transform into supramolecular structures, can have a direct impact on the... More

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    Summary
    The daily diet is important for our survival, health, and wellbeing. Functional food materials, which tailor the digestion process, can help maintaining and even improving human health and lifestyle. Knowledge on how food products, particularly food emulsions such as milk, interact with the digestive system, where they transform into supramolecular structures, can have a direct impact on the rational design of such advanced materials for functional food delivery applications. These materials have the potential to be personalized to digestive conditions and dietary nutrient requirements of the consumer or patient. They could help maintaining the uptake of codelivered nutrients and drugs even under compromised digestion conditions such as a fat maldigestion, a low bile salt concentration, or a limited lipase action. Such conditions are found, for instance, in preterm infants or patients with digestive disorders such as chronic pancreatitis or pancreatic insufficiency. Tailored nanostructure formation and transformation in these materials may further trigger the digestion rate and thus have an impact on the related feeling of satiety, which may help curing eating disorders and reduce the societal challenges of obesity and related diseases. In this contribution, the specific focus is set on discussing the equilibrium and dynamic colloidal properties of food emulsion droplets during digestion and their implications for designing nature- inspired functional food materials. These investigations provide a perspective toward the design of personalized food colloids.