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A PET/CT-follow-up imaging study to differentiate takotsubo cardiomyopathy from acute myocardial infarction

Ghadri, Jelena ; Dougoud, Svetlana ; Maier, Willibald ; Kaufmann, Philipp ; Gaemperli, Oliver ; Prasad, Abhiram ; Lüscher, Thomas ; Templin, Christian

In: The International Journal of Cardiovascular Imaging, 2014, vol. 30, no. 1, p. 207-209

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    Title
    • A PET/CT-follow-up imaging study to differentiate takotsubo cardiomyopathy from acute myocardial infarction
    Author
    • Ghadri, Jelena. Department of Cardiology, Cardiovascular Center, University Hospital Zurich, Ramistrasse 100, D-Rämi, 8091, Zurich, Switzerland
    • Dougoud, Svetlana. Cardiac Imaging Divison, Department of Radiology, University Hospital Zurich, Zurich, Switzerland
    • Maier, Willibald. Department of Cardiology, Cardiovascular Center, University Hospital Zurich, Ramistrasse 100, D-Rämi, 8091, Zurich, Switzerland
    • Kaufmann, Philipp. Cardiac Imaging Divison, Department of Radiology, University Hospital Zurich, Zurich, Switzerland
    • Gaemperli, Oliver. Department of Cardiology, Cardiovascular Center, University Hospital Zurich, Ramistrasse 100, D-Rämi, 8091, Zurich, Switzerland
    • Prasad, Abhiram. Division of Cardiovascular Diseases, Mayo Clinic Rochester, Rochester, MN, USA
    • Lüscher, Thomas. Department of Cardiology, Cardiovascular Center, University Hospital Zurich, Ramistrasse 100, D-Rämi, 8091, Zurich, Switzerland
    • Templin, Christian. Department of Cardiology, Cardiovascular Center, University Hospital Zurich, Ramistrasse 100, D-Rämi, 8091, Zurich, Switzerland
    Document Type
    • Postprint
    Language
    • English
    Published in
    • The International Journal of Cardiovascular Imaging, 2014, vol. 30, no. 1, p. 207-209. Springer Netherlands
    Other Version
    OAI-PMH Identifier
    • oai:doc.rero.ch:325834
    Summary
    Takotsubo cardiomyopathy (TTC) is still an under-recognized disease and little data exists on the coexistence of TTC and obstructive coronary artery disease. Our patient case of an 80-year-old female lady highlights the impact of a positron emission tomography/computed tomography (PET/CT) follow-up imaging study to delineate this unique entity from acute coronary syndrome (ACS). Furthermore, we show for the first time that coronary flow reserve and myocardial blood flow is globally impaired in TTC and not only restricted to the non-contracting parts. This indicates a global microcirculatory impairment effect of the heart in the acute stage of TTC. Our case also demonstrates that a transient metabolic defect is also involved in this disease. Follow-up imaging by PET/CT in our patient case unmasked TTC and facilitated to exclude the differential diagnosis of ACS.