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Intraoperative fabrication of patient-specific moulded implants for skull reconstruction: single-centre experience of 28 cases

Stieglitz, Lennart ; Gerber, Nicolas ; Schmid, Thomas ; Mordasini, Pasquale ; Fichtner, Jens ; Fung, Christian ; Murek, Michael ; Weber, Stefan ; Raabe, Andreas ; Beck, Jürgen

In: Acta Neurochirurgica, 2014, vol. 156, no. 4, p. 793-803

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    Title
    • Intraoperative fabrication of patient-specific moulded implants for skull reconstruction: single-centre experience of 28 cases
    Author
    • Stieglitz, Lennart. Department of Neurosurgery, Bern University Hospital, Freiburgstrasse 10, 3010, Bern, Switzerland
    • Gerber, Nicolas. ARTORG-ISTB, University of Bern, Bern, Switzerland
    • Schmid, Thomas. University of Bern, Bern, Switzerland
    • Mordasini, Pasquale. Diagnostic and Interventional Neuroradiology, Bern University Hospital, Bern, Switzerland
    • Fichtner, Jens. Department of Neurosurgery, Bern University Hospital, Freiburgstrasse 10, 3010, Bern, Switzerland
    • Fung, Christian. Department of Neurosurgery, Bern University Hospital, Freiburgstrasse 10, 3010, Bern, Switzerland
    • Murek, Michael. Department of Neurosurgery, Bern University Hospital, Freiburgstrasse 10, 3010, Bern, Switzerland
    • Weber, Stefan. ARTORG-ISTB, University of Bern, Bern, Switzerland
    • Raabe, Andreas. Department of Neurosurgery, Bern University Hospital, Freiburgstrasse 10, 3010, Bern, Switzerland
    • Beck, Jürgen. Department of Neurosurgery, Bern University Hospital, Freiburgstrasse 10, 3010, Bern, Switzerland
    Document Type
    • Postprint
    OAI-PMH Identifier
    • oai:doc.rero.ch:324776
    Summary
    Background: Intraoperatively fabricated polymethylmethacrylate (PMMA) implants based on computer-designed moulds were used to improve cosmetic results after hard tissue replacement. To assess the implant's cosmetic and functional results we performed both subjective and objective assessments. Methods: This retrospective analysis was performed using a cohort of 28 patients who received PMMA implants between February 2009 and March 2012. The cosmetic and functional results were assessed using a patient questionnaire. Furthermore an objective volumetric subtraction score (0-100) was applied and implant thickness, as well as gaps and tiers, were measured. Results: Patients mainly judged their cosmetic result as "good”. Two of the 28 patients found their cosmetic result unfavourable. The functional result and stability was mainly judged to be good. Measurements of implant thickness showed a very high correlation with the thickness of the contralateral bone. Volumetric subtraction led to a median quality of 80 on a scale from 0 to 100. Median gaps around the margins of the implant were 1.5mm parietally, 1.7mm frontally and 3.5mm fronto-orbitally, and median tiers were 1.2mm, 0mm and 0mm respectively. The overall rate of surgical revisions was 10.7% (three patients). Two patients suffered from wound healing disturbances (7.1%). The overall complication rate was comparable to other reports in the literature. Conclusions: Implantation of intraoperatively fabricated patient-specific moulded implants is a cost-effective and safe technique leading to good clinical results with a low complication rate.