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Pediatric papillary tumors of the pineal region: to observe or to treat following gross total resection?

Abela, Lucia ; Rushing, Elisabeth ; Ares, Carmen ; Scheer, Ianina ; Bozinov, Oliver ; Boltshauser, Eugen ; Grotzer, Michael

In: Child's Nervous System, 2013, vol. 29, no. 2, p. 307-310

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    Titre
    • Pediatric papillary tumors of the pineal region: to observe or to treat following gross total resection?
    Auteur
    • Abela, Lucia. Department of Oncology, University Children's Hospital of Zurich, Zurich, Switzerland
    • Rushing, Elisabeth. Institute of Neuropathology, University Hospital of Zurich, Zurich, Switzerland
    • Ares, Carmen. Center for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland
    • Scheer, Ianina. Department of Diagnostic Imaging, University Children's Hospital of Zurich, Zurich, Switzerland
    • Bozinov, Oliver. Department of Neurosurgery, University Hospital of Zurich, Zurich, Switzerland
    • Boltshauser, Eugen. Department of Neurology, University Children's Hospital of Zurich, Zurich, Switzerland
    • Grotzer, Michael. Department of Oncology, University Children's Hospital of Zurich, Zurich, Switzerland
    Type de document
    • Postprint
    Identifiant OAI-PMH
    • oai:doc.rero.ch:321344
    Summary
    Introduction: Papillary tumors of the pineal region (PTPR) are rare brain tumors characterized by frequent local recurrences. Standardized treatment strategies are not yet defined. Case report: We present the case of a 3-year-old girl diagnosed with PTPR. Due to her young age, adjuvant radiotherapy was omitted after gross total tumor resection. Thirty-six months later, local tumor recurrence occurred. Considering the possible risks of secondary surgery, the recurrent tumor was irradiated with proton radiotherapy. Three months later, the tumor showed near-complete remission. Discussion: Based on this experience and other pediatric case reports from the literature, local radiotherapy might be suggested also after complete tumor resection