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Second primary squamous cell carcinoma arising in cutaneous flap reconstructions of two head and neck cancer patients

Monnier, Yan ; Pasche, Philippe ; Monnier, Philippe ; Andrejevic-Blant, Snezana

In: European Archives of Oto-Rhino-Laryngology, 2008, vol. 265, no. 7, p. 831-835

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    Titre
    • Second primary squamous cell carcinoma arising in cutaneous flap reconstructions of two head and neck cancer patients
    Auteur
    • Monnier, Yan. Institute of Pathology, Centre Hospitalier Universitaire Vaudois (CHUV), Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 25, 1011, Lausanne, Switzerland
    • Pasche, Philippe. Otolaryngology, Head, and Neck Surgery Department, Centre Hospitalier Universitaire Vaudois (CHUV), Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland
    • Monnier, Philippe. Otolaryngology, Head, and Neck Surgery Department, Centre Hospitalier Universitaire Vaudois (CHUV), Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland
    • Andrejevic-Blant, Snezana. Institute of Pathology, Centre Hospitalier Universitaire Vaudois (CHUV), Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 25, 1011, Lausanne, Switzerland
    Type de document
    • Postprint
    Langue
    • Inglese
    Publié dans
    • European Archives of Oto-Rhino-Laryngology, 2008, vol. 265, no. 7, p. 831-835. Springer-Verlag
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:321048
    Summary
    Early complications of myocutaneous flap transfers following surgical eradication of head and neck tumors have been extensively described. However, knowledge concerning long-term complications of these techniques remains limited. We report the cases of two patients with a prior history of squamous cell carcinoma of the head and neck (HNSCC), who developed a second primary SCC on the cutaneous surface of their flaps, years after reconstruction. Interestingly, it seems that the well-known risk of a second primary SCC in patients with previous head and neck carcinoma also applies to foreign tissues implanted within the area at risk. Given the important expansion of these interventions, this type of complication may become more frequent in the future. Therefore, long-term follow-up of patients previously treated for HNSCC not only requires careful evaluation of the normal mucosa of the upper aero-digestive tract, but also of the cutaneous surface of the flap used for reconstruction