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Dural arachnoid granulations and "giant” arachnoid granulations

Haybaeck, Johannes ; Silye, Rene ; Soffer, Dov

In: Surgical and Radiologic Anatomy, 2008, vol. 30, no. 5, p. 417-421

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    Titre
    • Dural arachnoid granulations and "giant” arachnoid granulations
    Auteur
    • Haybaeck, Johannes. Department of Pathology and Neuropathology, State Neuropsychiatric Hopsital Wagner-Jauregg, Wagner-Jauregg-Weg 15, 4020, Linz, Austria
    • Silye, Rene. Department of Pathology and Neuropathology, State Neuropsychiatric Hopsital Wagner-Jauregg, Wagner-Jauregg-Weg 15, 4020, Linz, Austria
    • Soffer, Dov. Institute of Neuropathology, Department of Pathology, University Hospital Zürich, Schmelzbergstrasse 12, 8091, Zurich, Switzerland
    Type de document
    • Postprint
    Langue
    • Inglese
    Publié dans
    • Surgical and Radiologic Anatomy, 2008, vol. 30, no. 5, p. 417-421. Springer-Verlag
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:320702
    Summary
    Although arachnoid granulations (AGs) were already described by Antonio Pacchioni more than 300years ago, two issues draw particular attention: first, the radiological features and differential diagnosis of the so-called giant AGs (GAGs) and second, their possible association with various disease processes. In order to evaluate the frequency, size and normal distribution of GAGs, an anatomical study of the dural sinuses was carried out. It involved all the autopsies performed during the period August 2002-February 2005 and included 651 cases: 306 females and 345 males, aged 13-99years (mean 69years). Grossly visible GAGs were identified in 24 cases: 7 females and 17 males, aged 45-92years (mean 69years). This is the largest population-based anatomical study on GAGs. It shows that GAGs, in general a rare finding (3.68%), are rather common in the adult population, especially in the elderly (aged >65years) and that they can reach remarkable size (up to 2.5cm and more in diameter). Giant AGs should be considered in the radiological differential diagnosis of intradural lesions, particularly those occurring in the transverse sinus of the elderly