Fulltext

Platelet Inhibition in Percutaneous Coronary Interventions = Plättchenhemmung bei perkutanen Koronarinterventionen

Wyss, Christophe ; Roffi, Marco

In: Herz Kardiovaskuläre Erkrankungen, 2005, vol. 30, no. 3, p. 189-196

Zum persönliche Liste hinzufügen
    Titel
    • Platelet Inhibition in Percutaneous Coronary Interventions
    Titel Übersetzung ()
    • Plättchenhemmung bei perkutanen Koronarinterventionen
    Autor
    • Wyss, Christophe
    • Roffi, Marco. Department of Cardiology, University Hospital, Zurich, Switzerland
    Dokumententyp
    • Postprint
    Sprache
    • Englisch
    Veröffentlicht in
    • Herz Kardiovaskuläre Erkrankungen, 2005, vol. 30, no. 3, p. 189-196. Urban & Vogel
    Andere elektronische Ausgabe
    OAI-PMH-ID
    • oai:doc.rero.ch:320075
    Summary
    Abstract : Mechanical disruption of atherosclerotic plaques at the time of percutaneous coronary intervention (PCI) is a potent stimulus for arterial thrombosis. Since platelets play a crucial role in the cascade of clot formation, platelet inhibition is an essential step for successful PCI. Aspirin remains the cornerstone of any antithrombotic regimen in the interventional setting. The addition of a thienopyridine is mandatory following stenting to prevent thrombosis of the device. Whenever possible, patients undergoing PCI should be pretreated with clopidogrel and the drug should be continued for up to 1 year. Glycoprotein IIb/IIIa antagonists should be administered in high-risk patients, such as those with acute coronary syndromes, diabetes, or complex coronary anatomy