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Follow-up of the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA 2) 1991-2003: methods and characterization of participants

Ackermann-Liebrich, Ursula ; Kuna-Dibbert, Birgit ; Probst-Hensch, Nicole ; Schindler, Christian ; Dietrich, Denise ; Stutz, Elisabeth ; Bayer-Oglesby, Lucy ; Baum, Felix ; Brändli, Otto ; Brutsche, Martin ; Downs, Sara ; Keidel, Dirk ; Gerbase, Margaret ; Imboden, Medea ; Keller, Roland ; Knöpfli, Bruno ; Künzli, Nino ; Nicod, Laurent ; Pons, Marco ; Staedele, Patricia ; Tschopp, Jean-Marie ; Zellweger, Jean-Pierre ; Leuenberger, Philippe

In: Sozial- und Präventivmedizin/Social and Preventive Medicine, 2005, vol. 50, no. 4, p. 245-263

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    Titre
    • Follow-up of the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA 2) 1991-2003: methods and characterization of participants
    Auteur
    • Ackermann-Liebrich, Ursula. Institute of Social and Preventive Medicine, University of Basel, Steinengraben 49, Basel, CH-4051, Switzerland
    • Kuna-Dibbert, Birgit. Institute of Social and Preventive Medicine, University of Basel, Steinengraben 49, Basel, CH-4051, Switzerland
    • Probst-Hensch, Nicole. Molecular Epidemiology/Cancer Registry, Institute of Social and Preventive Medicine/Dept. of Pathology, University of Zürich, Switzerland
    • Schindler, Christian. Institute of Social and Preventive Medicine, University of Basel, Steinengraben 49, Basel, CH-4051, Switzerland
    • Dietrich, Denise. Institute of Social and Preventive Medicine, University of Basel, Steinengraben 49, Basel, CH-4051, Switzerland
    • Stutz, Elisabeth. Institute of Social and Preventive Medicine, University of Basel, Steinengraben 49, Basel, CH-4051, Switzerland
    • Bayer-Oglesby, Lucy. Institute of Social and Preventive Medicine, University of Basel, Steinengraben 49, Basel, CH-4051, Switzerland
    • Baum, Felix. Institute of Social and Preventive Medicine, University of Basel, Steinengraben 49, Basel, CH-4051, Switzerland
    • Brändli, Otto. Zürcher Höhenklinik, Wald, Switzerland
    • Brutsche, Martin. Dept of Pulmonology, University Hospital Basel, Switzerland
    • Downs, Sara. Institute of Social and Preventive Medicine, University of Basel, Steinengraben 49, Basel, CH-4051, Switzerland
    • Keidel, Dirk. Institute of Social and Preventive Medicine, University of Basel, Steinengraben 49, Basel, CH-4051, Switzerland
    • Gerbase, Margaret. Pulmonology Service, University Hospital of Geneva, Switzerland
    • Imboden, Medea. Molecular Epidemiology/Cancer Registry, Institute of Social and Preventive Medicine/Dept. of Pathology, University of Zürich, Switzerland
    • Keller, Roland. Lung Clinic at Schachen, Aarau, Switzerland
    • Knöpfli, Bruno. Alpine Children's Hospital, Davos, Switzerland
    • Künzli, Nino. Division of Occupational and Environmental Health, University of Southern California, United States of America
    • Nicod, Laurent. Pulmonology Service, "Inselspital” Bern, Switzerland
    • Pons, Marco. Pulmonology Service, Hospital of Lugano, Switzerland
    • Staedele, Patricia. Institute of Social and Preventive Medicine, University of Basel, Steinengraben 49, Basel, CH-4051, Switzerland
    • Tschopp, Jean-Marie. Centre Valaisan de Pneumologie, Montana, Switzerland
    • Zellweger, Jean-Pierre. Service of Pulmonology, CHUV, University Hospital of Lausanne, Switzerland
    • Leuenberger, Philippe. Service of Pulmonology, CHUV, University Hospital of Lausanne, Switzerland
    Type de document
    • Postprint
    Langue
    • Inglese
    Publié dans
    • Sozial- und Präventivmedizin/Social and Preventive Medicine, 2005, vol. 50, no. 4, p. 245-263. Birkhäuser-Verlag; www.birkhauser.ch
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:318336
    Summary
    Summary.: Objectives: The Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA) was designed to investigate the health effects from long-term exposure to air pollution. Methods: The health assessment at recruitment (1991) and at the first reassessment (2001-3) consisted of an interview about respiratory health, occupational and other exposures, spirometry, a methacholine bronchial challenge test, end-expiratory carbon monoxide (CO) measurement and measurement for atopy. A bio bank for DNA and blood markers was established. Heart rate variability was measured using a 24-hour ECG (Holter) in a random sample of participants aged 50years and older. Concentrations of nitrogen dioxide (NO2), sulphur dioxide (SO2), ozone (O3) and particulates in ambient air have been monitored in all study areas since 1991. Residential histories collected over the 11year follow-up period coupled with GIS modelling will provide individual long-term air pollutant exposure estimates. Results: Of 9651 participants examined in 1991, 8715 could be traced for the cohort study and 283 died. Basic information about health status was obtained for 8047 individuals (86% of alive persons), 6528 individuals (70%) agreed to the health examination and 5973 subjects (62%) completed the entire protocol. Non-participants in the reassessment were on average younger than participants and more likely to have been smokers and to have reported respiratory symptoms in the first assessment. Average weight had increased by 5.5kg in 11years and 28% of smokers in 1991 had quit by the time of the reassessment