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Ganciclovir for Severe Cytomegalovirus Primary Infection in an Immunocompetent Child

Hadaya, K. ; Kaiser, L. ; Rubbia-Brandt, L. ; Gervaix, A. ; Diana, A.

In: European Journal of Clinical Microbiology and Infectious Diseases, 2004, vol. 23, no. 3, p. 218-220

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    Titre
    • Ganciclovir for Severe Cytomegalovirus Primary Infection in an Immunocompetent Child
    Auteur
    • Hadaya, K.. Central Laboratory of Virology, Division of Infectious Diseases, Department of Internal Medicine, University Hospitals of Geneva, Geneva, Switzerland
    • Kaiser, L.. Central Laboratory of Virology, Division of Infectious Diseases, Department of Internal Medicine, University Hospitals of Geneva, Geneva, Switzerland
    • Rubbia-Brandt, L.. Department of Pathology, University Hospitals of Geneva, Geneva, Switzerland
    • Gervaix, A.. Department of Pediatrics, University Hospitals of Geneva, Geneva, Switzerland
    • Diana, A.. Department of Pediatrics, University Hospitals of Geneva, Geneva, Switzerland
    Type de document
    • Postprint
    Langue
    • Inglese
    Publié dans
    • European Journal of Clinical Microbiology and Infectious Diseases, 2004, vol. 23, no. 3, p. 218-220. Springer-Verlag
    Autre version électronique
    Classification
    • Santé
    Identifiant OAI-PMH
    • oai:doc.rero.ch:317014
    Summary
    Described here is the unusual case of a previously healthy 17-month-old girl who developed severe cytomegalovirus (CMV) disease with prolonged fever and hepatitis. The severity of her illness required hospitalization and prompted antiviral treatment. Short-term intravenous ganciclovir treatment was associated with immediate and sustained resolution of the symptoms as well as a sharp decrease of CMV viremia. This observation suggests that antiviral therapy might be considered in select cases of severe primary CMV infection in immunocompetent children