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Recovery of renal function after long-term dialysis in hemolytic uremic syndrome

Brunner, Kathrin ; Bianchetti, Mario ; Neuhaus, Thomas

In: Pediatric Nephrology, 2004, vol. 19, no. 2, p. 229-231

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    Titre
    • Recovery of renal function after long-term dialysis in hemolytic uremic syndrome
    Auteur
    • Brunner, Kathrin. Division of Pediatric Nephrology, University of Bern, Bern, Switzerland
    • Bianchetti, Mario. Division of Pediatric Nephrology, University of Bern, Bern, Switzerland
    • Neuhaus, Thomas. Division of Pediatric Nephrology, University of Zurich, Zurich, Switzerland
    Type de document
    • Postprint
    Identifiant OAI-PMH
    • oai:doc.rero.ch:316718
    Summary
    Long-lasting recovery of renal function of the native kidneys after prolonged renal replacement therapy is rare. An 8-year-old girl and a 3-year-old boy had suffered from acute atypical and diarrhea-associated hemolytic uremic syndrome (HUS), respectively, with subsequent apparent end-stage renal failure. Both recovered renal function after long-lasting anuria and dialysis of 8 and 16months, respectively. After prolonged follow-up, i.e., 7 and 5years after cessation of dialysis, they attained normal or slightly reduced renal function (plasma creatinine 84 and 90µmol/l, respectively). In addition, growth and cognitive development were normal. We conclude that caution is appropriate before offering early renal transplantation to pediatric patients with presumed end-stage kidney disease secondary to HUS