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Recent emergence of the wheat Lr34 multi-pathogen resistance: insights from haplotype analysis in wheat, rice, sorghum and Aegilops tauschii

Krattinger, Simon ; Jordan, David ; Mace, Emma ; Raghavan, Chitra ; Luo, Ming-Cheng ; Keller, Beat ; Lagudah, Evans

In: Theoretical and Applied Genetics, 2013, vol. 126, no. 3, p. 663-672

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    Titre
    • Recent emergence of the wheat Lr34 multi-pathogen resistance: insights from haplotype analysis in wheat, rice, sorghum and Aegilops tauschii
    Auteur
    • Krattinger, Simon. CSIRO Plant Industry, GPO Box 1600, 2601, Canberra, ACT, Australia
    • Jordan, David. Queensland Alliance for Agriculture and Food Innovation, Hermitage Research Facility, The University of Queensland, 4370, Warwick, QLD, Australia
    • Mace, Emma. Department of Agriculture, Fisheries and Forestry, Hermitage Research Facility, Agri-Science Queensland, 604 Yangan Road, 4370, Warwick, QLD, Australia
    • Raghavan, Chitra. Plant Breeding, Genetics, and Biotechnology Division, International Rice Research Institute, DAPO, P.O. Box 7777, Metro Manila, Philippines
    • Luo, Ming-Cheng. Department of Plant Sciences, University of California, 95616, Davis, CA, USA
    • Keller, Beat. Institute of Plant Biology, University of Zurich, Zollikerstr. 107, 8008, Zurich, Switzerland
    • Lagudah, Evans. CSIRO Plant Industry, GPO Box 1600, 2601, Canberra, ACT, Australia
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • Theoretical and Applied Genetics, 2013, vol. 126, no. 3, p. 663-672. Springer-Verlag
    Autre version électronique
    Classification
    • Agriculture, Agronomie
    Identifiant OAI-PMH
    • oai:doc.rero.ch:315684
    Summary
    Spontaneous sequence changes and the selection of beneficial mutations are driving forces of gene diversification and key factors of evolution. In highly dynamic co-evolutionary processes such as plant-pathogen interactions, the plant's ability to rapidly adapt to newly emerging pathogens is paramount. The hexaploid wheat gene Lr34, which encodes an ATP-binding cassette (ABC) transporter, confers durable field resistance against four fungal diseases. Despite its extensive use in breeding and agriculture, no increase in virulence towards Lr34 has been described over the last century. The wheat genepool contains two predominant Lr34 alleles of which only one confers disease resistance. The two alleles, located on chromosome 7DS, differ by only two exon-polymorphisms. Putatively functional homoeologs and orthologs of Lr34 are found on the B-genome of wheat and in rice and sorghum, but not in maize, barley and Brachypodium. In this study we present a detailed haplotype analysis of homoeologous and orthologous Lr34 genes in genetically and geographically diverse selections of wheat, rice and sorghum accessions. We found that the resistant Lr34 haplotype is unique to the wheat D-genome and is not found in the B-genome of wheat or in rice and sorghum. Furthermore, we only found the susceptible Lr34 allele in a set of 252 Ae. tauschii genotypes, the progenitor of the wheat D-genome. These data provide compelling evidence that the Lr34 multi-pathogen resistance is the result of recent gene diversification occurring after the formation of hexaploid wheat about 8,000years ago