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Clinical evaluation of a breathing protocol for PET/CT

de Juan, Ramon ; Seifert, Burkhardt ; Berthold, Thomas ; von Schulthess, Gustav ; Goerres, Gerhard

In: European Radiology, 2004, vol. 14, no. 6, p. 1118-1123

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    Titel
    • Clinical evaluation of a breathing protocol for PET/CT
    Autor
    • de Juan, Ramon. Division of Nuclear Medicine, University Hospital Zurich, 8091, Zurich, Switzerland
    • Seifert, Burkhardt. Department of Biostatistics, University of Zurich, Zurich, Switzerland
    • Berthold, Thomas. Division of Nuclear Medicine, University Hospital Zurich, 8091, Zurich, Switzerland
    • von Schulthess, Gustav. Division of Nuclear Medicine, University Hospital Zurich, 8091, Zurich, Switzerland
    • Goerres, Gerhard. Division of Nuclear Medicine, University Hospital Zurich, 8091, Zurich, Switzerland
    Dokumententyp
    • Postprint
    Sprache
    • Englisch
    Veröffentlicht in
    • European Radiology, 2004, vol. 14, no. 6, p. 1118-1123. Springer-Verlag
    Andere elektronische Ausgabe
    OAI-PMH-ID
    • oai:doc.rero.ch:313890
    Summary
    The aim of this study was to assess the frequency and severity of respiration-induced curvilinear respiration artifacts (RICA) on co-registered positron emission tomography/computed tomography (PET/CT) images acquired on a combined PET/CT scanner before and after modifying the respiration protocol for CT scanning, with retrospective analysis of two groups of 100 patients each, before and after implementing a respiration protocol with breath-hold (BH) in the normal expiration position for the acquisition of the CT images. The CT data were used as attenuation map and for image co-registration. A ranking of co-registered PET/CT and PET images (including maximum intensity projection) was done by two observers in consensus using a scale from 0 to 3. Zero indicated that no RICA was visible and 1, 2, and 3 described artifact with increasing severity. A significant difference in RICA occurrence was found between the two groups (p<0.0001). There was a 45% decrease of artifact frequency when using the normal expiration protocol and a 68% decrease of grade-2 and grade-3 artifacts (p=0.004). The results of this study suggest that BH during the normal expiration position for CT scanning can be recommended to reduce the occurrence and the severity of RICA on PET/CT