First in vivo head-to-head comparison of high-definition versus standard-definition stent imaging with 64-slice computed tomography

Fuchs, Tobias ; Stehli, Julia ; Fiechter, Michael ; Dougoud, Svetlana ; Sah, Bert-Ram ; Gebhard, Cathérine ; Bull, Sacha ; Gaemperli, Oliver ; Kaufmann, Philipp

In: The International Journal of Cardiovascular Imaging, 2013, vol. 29, no. 6, p. 1409-1416

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    The aim of this study was to compare image quality characteristics from 64-slice high definition (HDCT) versus 64-slice standard definition CT (SDCT) for coronary stent imaging. In twenty-five stents of 14 patients, undergoing contrast-enhanced CCTA both on 64-slice SDCT (LightSpeedVCT, GE Healthcare) and HDCT (Discovery HD750, GE Healthcare), radiation dose, contrast, noise and stent characteristics were assessed. Two blinded observers graded stent image quality (score 1=no, 2=mild, 3=moderate, and 4=severe artefacts). All scans were reconstructed with increasing contributions of adaptive statistical iterative reconstruction (ASIR) blending (0, 20, 40, 60, 80 and 100%). Image quality was significantly superior in HDCT versus SDCT (score 1.7±0.5 vs. 2.7±0.7; p<0.05). Image noise was significantly higher in HDCT compared to SDCT irrespective of ASIR contributions (p<0.05). Addition of 40% ASIR or more reduced image noise significantly in both HDCT and SDCT. In HDCT in-stent luminal attenuation was significantly lower and mean measured in-stent luminal diameter was significantly larger (1.2±0.4mm vs. 0.8±0.4mm; p<0.05) compared to SDCT. Radiation dose from HDCT was comparable to SDCT (1.8±0.7mSv vs. 1.7±0.7mSv; p=ns). Use of HDCT for coronary stent imaging reduces partial volume artefacts from stents yielding improved image quality versus SDCT at a comparable radiation dose