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Influence of serum supplemented cell culture medium on colloidal stability of polymer coated iron oxide and polystyrene nanoparticles with impact on cell interactions in vitro

  • Hirsch, Vera Adolphe Merkle Institute, Marly, Switzerland - University of Fribourg, Department of Chemistry, Switzerland
  • Salaklang, Jatuporn Adolphe Merkle Institute, Marly, Switzerland
  • Rothen-Rutishauser, Barbara Adolphe Merkle Institute, Marly, Switzerland - Respiratory Medicine, Bern University Hospital, Switzerland
  • Petri-Fink, Alke Adolphe Merkle Institute, Marly, Switzerland - University of Fribourg, Department of Chemistry, Switzerland
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    19.12.2012
Published in:
  • IEEE Transactions on Magnetics. - 2012, vol. 49, no. 1, p. 402-407
Colloidal stability
PVA-SPIONs
nanoparticle-cell interactions
polystyrene-NPs
surface charge
English When nanoparticles interact with cells, the possible cellular responses to the particles depend on an array of parameters, in both particle and biological aspects. On the one hand, the physicochemical properties of the particles (e.g., material, size, shape, and surface charge) are known to play a key role in particle-cell interactions. On the other hand, it has been shown that prior to coming into contact with cells, nanoparticle interaction with the surrounding biological fluid may lead to a change of the initial particle properties. For example, the colloidal behavior of nanoparticles is strongly influenced by the density and viscosity of the surrounding media in both in vitro and in vivo systems.
Faculty
Faculté des sciences et de médecine
Department
Département de Chimie
Language
  • English
Classification
Chemistry
License
License undefined
Identifiers
Persistent URL
https://folia.unifr.ch/unifr/documents/302826
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