Fulltext

Detection of liver metastases under 2cm: comparison of different acquisition protocols in four row multidetector-CT (MDCT)

Abdelmoumene, Amina ; Chevallier, Patrick ; Chalaron, Marc ; Schneider, Frédéric ; Verdun, Francis ; Frascarolo, Phillipe ; Meuli, Reto ; Schnyder, Pierre ; Denys, Alban

In: European Radiology, 2005, vol. 15, no. 9, p. 1881-1887

Aggiungi alla tua lista
    Titre
    • Detection of liver metastases under 2cm: comparison of different acquisition protocols in four row multidetector-CT (MDCT)
    Auteur
    • Abdelmoumene, Amina. Department of Diagnostic and Interventional Radiology, University Hospital Centre (CHUV), 1011, Lausanne, Switzerland
    • Chevallier, Patrick. Department of Diagnostic and Interventional Radiology, University Hospital Centre (CHUV), 1011, Lausanne, Switzerland
    • Chalaron, Marc. Department of Diagnostic and Interventional Radiology, University Hospital Centre (CHUV), 1011, Lausanne, Switzerland
    • Schneider, Frédéric. Department of Diagnostic and Interventional Radiology, University Hospital Centre (CHUV), 1011, Lausanne, Switzerland
    • Verdun, Francis. University Institute for Applied Radiophysics, Grand-Pré 1, 1007, Lausanne, Switzerland
    • Frascarolo, Phillipe. Department of Anaesthesiology, University Hospital Centre (CHUV), 1011, Lausanne, Switzerland
    • Meuli, Reto. Department of Diagnostic and Interventional Radiology, University Hospital Centre (CHUV), 1011, Lausanne, Switzerland
    • Schnyder, Pierre. Department of Diagnostic and Interventional Radiology, University Hospital Centre (CHUV), 1011, Lausanne, Switzerland
    • Denys, Alban. Department of Diagnostic and Interventional Radiology, University Hospital Centre (CHUV), 1011, Lausanne, Switzerland
    Type de document
    • Postprint
    Langue
    • Inglese
    Publié dans
    • European Radiology, 2005, vol. 15, no. 9, p. 1881-1887. Springer-Verlag; http://www.springer.de
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:311430
    Summary
    This study compared different acquisition protocols performance to detect small liver metastases (<2cm). Thirty consecutive patients with histologically proven hepatic metastases were explored by MDCT at the liver equilibrium phase by four successive acquisitions. We compared the following protocols (1-4): 5/30/1.5 (section thickness/table speed/pitch); 5/15/0.75; 5/11.25/0.75; and 2.5/15/1.5 with the same X-ray dose. The gold standard was based on patient radiological follow-up. Evolutive lesions were considered as true positive (TP). The described lesions, not found on the follow-up exams despite tumoral progression, were considered as false positive (FP). Stable lesions could not be considered as metastasis and were eliminated. One hundred and seventy-six lesions were detected: 61 TP and 91 FP. Twenty-four lesions were eliminated. The mean kappa values for protocols 1, 2, 3 and 4 were, respectively, 0.43, 0.68, 0.73 and 0.51 (0.61-0.80: substantial agreement) and the mean areas under the ROC curve were, respectively, 0.76, 0.87, 0.86 and 0.80. The results of protocols 2 and 3 were significantly superior to those of protocols 1 and 4. MDCT protocols using thin sections or an increased table speed are less efficient in detecting small metastases