Tick-borne encephalitis presenting as fever without localising signs—a case series

Meyer, Patrick ; Zimmermann, Hanspeter ; Goetschel, Philippe

In: European Journal of Pediatrics, 2010, vol. 169, no. 6, p. 767-769

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    Summary
    Introduction: Tick-borne encephalitis (TBE) presents without neurologic symptoms in 19% in children less than 16years in Switzerland (2000-2008). In these cases, fever can be the only leading manifestation. Case series: We report on four hospitalised children who had TBE and presented as fever without localising signs (FWLS) between 2000 and 2008 in an endemic area in Switzerland. Conclusion: TBE infection has to be considered in the differential diagnosis of FWLS in endemic areas. Foremost, FWLS characterised by a biphasic fever course and accompanied by headache in patients in a reduced general condition. Affirming that in patients presenting as FWLS also cases of TBE are contained, this disease is underreported