Emergence of an MDR Klebsiella pneumoniae ST231 producing OXA-232 and RmtF in Switzerland
- Mancini, Stefano Emerging Antibiotic Resistance Unit, Medical and Molecular, Microbiology, Department of Medicine, University of Fribourg, Switzerland
- Poirel, Laurent Emerging Antibiotic Resistance Unit, Medical and Molecular, Microbiology, Department of Medicine, University of Fribourg, Switzerland
- Tritten, Marie-Lise ADMED Microbiologie, La Chaux-de-Fonds, Switzerland
- Lienhard, Reto ADMED Microbiologie, La Chaux-de-Fonds, Switzerland
- Bassi, Cécile Médecine Interne, Hô pital du Jura Bernois, St-Imier, Switzerland
- Nordmann, Patrice Emerging Antibiotic Resistance Unit, Medical and Molecular, Microbiology, Department of Medicine, University of Fribourg, Switzerland - Institute of Microbiology, University of Lausanne and UniversityHospital Center, Lausanne, Switzerland
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2017
Published in:
- Journal of Antimicrobial Chemotherapy. - 2018, vol. 73, no. 3, p. 821-823
English
The increasing incidence of carbapenem-resistant Klebsiella pneumoniae is a major challenge to public health. Despite the fact that the prevalence of carbapenemases among carbapenem-resistant K. pneumoniae varies geographically, the incidence of OXA-48-like enzymes has soared in recent years and is particularly high in some European countries, such as Spain and France (74% and 78% among carbapenemase-producing K. pneumoniae, respectively).1 A significant number of OXA-48 variants have been reported in the last decade. This includes OXA-232, a carbapenemase firstly identified in France in 20112 and thereafter found in several countries.3,4 Recently, an MDR K. pneumoniae ST231 co-producing OXA-232, the ESBL CTX-M-15 and the 16S rRNA methyltransferase RmtF conferring broad- spectrum resistance to aminoglycosides has emerged as a successful epidemic...
- Faculty
- Faculté des sciences et de médecine
- Department
- Médecine 3ème année
- Language
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- English
- Classification
- Biological sciences
- License
- License undefined
- Identifiers
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- RERO DOC 306280
- DOI 10.1093/jac/dkx428
- Persistent URL
- https://folia.unifr.ch/unifr/documents/306216
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